Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | NMBR | P28336 | 8/20 | 0.45 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GP6 | Q9HCN6 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5881075 | 0.89 | NMBR (0.43) | TACR1NMBRPARP14TRPV1KDM4E | |
| SCHEMBL5880972 | 0.79 | NMBR (0.45) | TACR1NMBRPARP14MEN1KMT2A | |
| SCHEMBL5881086 | 0.78 | TACR1 (0.44) | TACR1NMBRCYP2C9CYP2C19 | |
| SCHEMBL5881092 | 0.78 | NMBR (0.44) | TACR1NMBRPARP14TRPV1MEN1 | |
| SCHEMBL5881261 | 0.77 | TACR1 (0.43) | TACR1NMBR | |
| SCHEMBL5881070 | 0.74 | TACR1 (0.42) | TACR1NMBRTRPV1 | |
| SCHEMBL5881088 | 0.73 | TACR1 (0.66) | TACR1NMBRTRPV1KDM4ECYP2C9 | |
| SCHEMBL5881263 | 0.72 | NMBR (0.44) | TACR1NMBRLMNA | |
| SCHEMBL5880965 | 0.70 | TACR1 (0.60) | TACR1NMBRTRPV1LMNAMAPT | |
| SCHEMBL5881032 | 0.68 | TACR1 (0.51) | TACR1NMBRKDM4EMEN1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122570-B2 | Tetrahydrocarbazol derivatives as ligands for G-protein-coupled receptors (GPCR) | ZENTARIS AG (DE) | 2006-10-17 | — | — | US | disclosed |