Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 16/20 | 0.48 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | GLP1R | P43220 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.48 |
| ▸ | OXTR | P30559 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL588265 | 0.90 | AVPR2 (0.48) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| SCHEMBL2502752 | 0.83 | AVPR2 (0.56) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| SCHEMBL583991 | 0.82 | AVPR2 (0.73) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| Hydrochloric Acid SCHEMBL7356821 | 0.74 | AVPR2 (0.63) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| SCHEMBL12744546 | 0.74 | AVPR2 (0.75) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| SCHEMBL582635 | 0.73 | AVPR2 (0.74) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| SCHEMBL582634 | 0.73 | AVPR2 (0.74) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| SCHEMBL583595 | 0.73 | AVPR2 (0.70) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| Hydrochloric Acid SCHEMBL583523 | 0.73 | AVPR2 (0.67) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| SCHEMBL15419822 | 0.73 | AVPR2 (0.79) | AVPR2AVPR1AABCB11ADRB2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170831-B1 | Benzazepine derivatives useful as vasopressin antagonists | OTSUKA PHARMA CO LTD (JP) | 2012-02-15 | — | — | EP | disclosed |