Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 6/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | NQO1 | P15559 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952821 | 1.00 | ERN1 (0.66) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL5546813 | 0.87 | ERN1 (0.64) | ERN1ALDH1A1 | |
| SCHEMBL8415236 | 0.86 | ERN1 (0.62) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL31166228 | 0.86 | ERN1 (0.62) | ERN1TRIM24TYRTRIM33CDK1 | |
| SCHEMBL1004413 | 0.86 | TYR (0.66) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL29708063 | 0.86 | TYR (0.66) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL1390736 | 0.84 | CDK1 (0.58) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL1185798 | 0.83 | ERN1 (0.67) | ERN1TRIM24TYRTRIM33CDK1 | |
| SCHEMBL7560250 | 0.82 | ERN1 (0.57) | ERN1CDK1LTA4H | |
| SCHEMBL9103188 | 0.82 | ERN1 (0.57) | ERN1CDK1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111100032-B | Preparation method and application of rare earth Schiff base complex containing ethoxy salicylaldehyde 1, 4-butanediamine | 陕西理工大学 | 2023-08-11 | — | — | CN | claimed |
| US-20230148641-A1 | FLAVOR COMPOSITION | FIRMENICH SA (CH) | 2023-05-18 | — | — | US | claimed |
| EP-4125427-A1 | FLAVOR COMPOSITION | Firmenich SA (CH) | 2023-02-08 | — | — | EP | claimed |
| CN-115279206-A | Flavor composition | 弗门尼舍有限公司 | 2022-11-01 | — | — | CN | claimed |
| WO-2021198199-A1 | FLAVOR COMPOSITION | FIRMENICH SA (CH) | 2021-10-07 | — | — | WO | claimed |
| CN-108358977-B | Preparation method and application of Schiff base complex of binuclear ruthenium | 陕西理工大学 | 2021-03-09 | — | — | CN | claimed |
| CN-111100032-A | Preparation method and application of rare earth Schiff base complex containing ethoxy salicylaldehyde 1, 4-butanediamine | 陕西理工大学 | 2020-05-05 | — | — | CN | claimed |
| CN-108358977-A | A kind of preparation method and applications of the Schiff base complex of double-core ruthenium | 陕西理工大学 | 2018-08-03 | — | — | CN | claimed |
| US-4473713-A | Hydrolysis of aryl-aliphatic ethers | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-09-25 | — | — | US | claimed |
| CN-118184642-A | Aromatic ring system heterocycle compound, and pharmaceutical composition and application thereof | 中国药科大学 | 2024-06-14 | — | — | CN | disclosed |
| CN-117886832-A | Benzoxazine-2-thioketone benzimidazole compound, and preparation method and medical application thereof | 徐州医科大学 | 2024-04-16 | — | — | CN | disclosed |
| CN-111100032-B | Preparation method and application of rare earth Schiff base complex containing ethoxy salicylaldehyde 1, 4-butanediamine | 陕西理工大学 | 2023-08-11 | — | — | CN | disclosed |
| US-11708344-B2 | Flavone derivatives for the treatment and prophylaxis of hepatitis B virus disease | HOFFMANN-LA ROCHE INC. (US) | 2023-07-25 | — | — | US | disclosed |
| US-20230148641-A1 | FLAVOR COMPOSITION | FIRMENICH SA (CH) | 2023-05-18 | — | — | US | disclosed |
| EP-0831836-A4 | SYNTHETIC CATALYTIC FREE RADICAL SCAVENGERS USEFUL AS ANTIOXIDANTS FOR PREVENTION AND THERAPY OF DISEASE | EUKARION INC (US) | 2000-09-27 | — | — | EP | disclosed |
| WO-2000035858-A1 | PHENYLGLYCINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-06-22 | — | — | WO | disclosed |
| EP-0831836-A1 | SYNTHETIC CATALYTIC FREE RADICAL SCAVENGERS USEFUL AS ANTIOXIDANTS FOR PREVENTION AND THERAPY OF DISEASE | EUKARION, INC. (US) | 1998-04-01 | — | — | EP | disclosed |
| US-4933497-A | Preparation of hydroxybenzaldehydes by hydrocarbonylation of halophenols | RHONE-POULENC CHIMIE (FR) | 1990-06-12 | — | — | US | disclosed |
| US-4473713-A | Hydrolysis of aryl-aliphatic ethers | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-09-25 | — | — | US | disclosed |
| US-4151183-A | OXIDATION OF TRIMETHYLPHENOL IN PRESENCE OF COMPLEX COBALT COMPOUND | RHONE POULENC, S.A. (FR) | 1979-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11708344-B2 | Flavone derivatives for the treatment and prophylaxis of hepatitis B virus disease | CCNE2, CCNE1, CCNT1 | ERN1 1445/4885ALDH1A1 455/4885TRIM24 2619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.