Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.67 |
| ▸ | PIM1 | P11309 | 2/20 | 0.58 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 6/20 | 0.54 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5884071 | 1.00 | PPARG (0.67) | PPARGPIM1PIM2KDM4EALDH1A1 | |
| SCHEMBL1847035 | 0.86 | PPARG (0.78) | PPARGPIM1PIM2KDM4EALDH1A1 | |
| SCHEMBL2260054 | 0.86 | PPARG (0.78) | PPARGPIM1PIM2KDM4EALDH1A1 | |
| SCHEMBL5111753 | 0.86 | PPARG (0.78) | PPARGPIM1PIM2KDM4EALDH1A1 | |
| SCHEMBL20005828 | 0.85 | PPARG (0.67) | PPARGPIM1PIM2KDM4EALDH1A1 | |
| SCHEMBL18103085 | 0.85 | PPARG (0.67) | PPARGPIM1PIM2KDM4EALDH1A1 | |
| SCHEMBL1850984 | 0.84 | PPARG (0.73) | PPARGPIM1PIM2KDM4EALDH1A1 | |
| SCHEMBL12520464 | 0.84 | PPARG (0.73) | PPARGPIM1PIM2KDM4EALDH1A1 | |
| SCHEMBL1850981 | 0.84 | PPARG (0.73) | PPARGPIM1PIM2KDM4EALDH1A1 | |
| SCHEMBL14084491 | 0.82 | PPARG (0.63) | PPARGPIM1PIM2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7001910-B1 | Thiazolidinedione derivatives as antidiabetic agents | VITA-INVEST S.A. (ES) | 2006-02-21 | — | — | US | disclosed |
| EP-1231211-B1 | THIAZOLIDINEDIONE DERIVATIVES AS ANTIDIABETIC AGENTS | VITA INVEST SA (ES) | 2003-05-28 | — | — | EP | disclosed |
| EP-1231211-A1 | THIAZOLIDINEDIONE DERIVATIVES AS ANTIDIABETIC AGENTS | VITA-INVEST, S.A. (ES) | 2002-08-14 | — | — | EP | disclosed |