Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 20/20 | 1.00 |
| ▸ | CNR1 | P21554 | 8/20 | 1.00 |
| ▸ | BCHE | P06276 | 3/20 | 0.73 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.73 |
| ▸ | ACHE | P22303 | 2/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5882005 | 1.00 | CNR2 (1.00) | CNR2CNR1BCHEOPRM1ACHE | |
| SCHEMBL5881694 | 1.00 | CNR2 (1.00) | CNR2CNR1BCHEOPRM1ACHE | |
| SCHEMBL5881941 | 0.98 | CNR2 (1.00) | CNR2CNR1BCHEOPRM1ACHE | |
| SCHEMBL5104557 | 0.92 | CNR2 (0.84) | CNR2CNR1BCHEOPRM1ACHE | |
| SCHEMBL14097660 | 0.92 | CNR2 (0.84) | CNR2CNR1BCHEOPRM1ACHE | |
| SCHEMBL5098449 | 0.92 | CNR2 (0.84) | CNR2CNR1BCHEOPRM1ACHE | |
| SCHEMBL5095710 | 0.89 | CNR2 (0.84) | CNR2CNR1BCHEOPRM1ACHE | |
| SCHEMBL5490824 | 0.89 | CNR2 (0.84) | CNR2CNR1BCHEOPRM1ACHE | |
| SCHEMBL25367619 | 0.88 | CNR2 (1.00) | CNR2CNR1BCHEOPRM1 | |
| SCHEMBL30641118 | 0.88 | CNR2 (1.00) | CNR2CNR1BCHEOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7030139-B2 | Compounds | ASTRAZENECA AB (SE) | 2006-04-18 | — | — | US | disclosed |
| US-20040116465-A1 | Novel compounds | ASTRAZENECA AB (SE) | 2004-06-17 | — | — | US | disclosed |