Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 4/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 11/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 11/20 | 0.40 |
| ▸ | MPL | P40238 | 2/20 | 0.39 |
| ▸ | RARB | P10826 | 2/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | RARG | P13631 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5687512 | 0.96 | KCNJ1 (0.48) | KCNJ1KCNH2CYP11B1CYP11B2RARB | |
| SCHEMBL5684738 | 0.95 | KCNJ1 (0.47) | KCNJ1KCNH2CYP11B1CYP11B2MPL | |
| SCHEMBL5683403 | 0.95 | KCNJ1 (0.47) | KCNJ1KCNH2CYP11B1CYP11B2MPL | |
| SCHEMBL5683412 | 0.93 | KCNJ1 (0.48) | KCNJ1KCNH2CYP11B1CYP11B2MPL | |
| SCHEMBL5684053 | 0.93 | KCNJ1 (0.50) | KCNJ1KCNH2CYP11B1CYP11B2 | |
| SCHEMBL5683808 | 0.91 | KCNJ1 (0.42) | KCNJ1KCNH2 | |
| SCHEMBL5683664 | 0.89 | KCNJ1 (0.48) | KCNJ1KCNH2CYP11B1CYP11B2MPL | |
| SCHEMBL5684106 | 0.89 | KCNJ1 (0.42) | KCNJ1KCNH2MPL | |
| SCHEMBL5684628 | 0.88 | KCNJ1 (0.47) | KCNJ1KCNH2CYP11B1CYP11B2MPL | |
| SCHEMBL5683940 | 0.88 | KCNJ1 (0.47) | KCNJ1KCNH2CYP11B1CYP11B2MPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100422124-C | Fused ring compound | DAINIPPON INK & CHEMICALS (JP) | 2008-10-01 | — | — | CN | disclosed |
| US-7067179-B1 | Fused ring compound | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2006-06-27 | — | — | US | disclosed |
| EP-1201632-A1 | FUSED RING COMPOUND | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2002-05-02 | — | — | EP | disclosed |