⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28550006 | 0.72 | — | — | |
| SCHEMBL30568094 | 0.72 | — | — | |
| SCHEMBL27819736 | 0.72 | — | — | |
| SCHEMBL29765179 | 0.72 | — | — | |
| Iodide SCHEMBL27607763 | 0.70 | — | — | |
| SCHEMBL28040869 | 0.67 | — | — | |
| SCHEMBL27819760 | 0.67 | — | — | |
| SCHEMBL27756223 | 0.67 | — | — | |
| SCHEMBL3794730 | 0.66 | — | — | |
| SCHEMBL27945472 | 0.63 | MAPT (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709723-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | GENZYME CORPORATION (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233544-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | GENZYME CORPORATION (US) | 2024-11-14 | — | — | WO | disclosed |
| CN-116354937-A | Pyridine (pyrimidine) amine derivative and application thereof | 江苏恩华药业股份有限公司 | 2023-06-30 | — | — | CN | disclosed |
| US-20150137051-A1 | NOVEL COMBINATION OF A HOST COMPOUND AND A DOPANT COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME | ROHM & HAAS ELECT MAT (KR) | 2015-05-21 | — | — | US | disclosed |
| EP-2847182-A1 | A NOVEL COMBINATION OF A HOST COMPOUND AND A DOPANT COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME | Rohm And Haas Electronic Materials Korea Ltd. (KR) | 2015-03-18 | — | — | EP | disclosed |
| WO-2014003440-A1 | A NOVEL COMBINATION OF A HOST COMPOUND AND A DOPANT COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2014-01-03 | — | — | WO | disclosed |
| US-7115617-B2 | Amino-substituted pyrimidinyl derivatives and methods of use | AMGEN INC. (US) | 2006-10-03 | — | — | US | disclosed |
| US-20030125346-A1 | Amino-substituted pyrimidinyl derivatives and methods of use | AMGEN INC. | 2003-07-03 | — | — | US | disclosed |