Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | BPTF | Q12830 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | PANK3 | Q9H999 | 2/20 | 0.33 |
| ▸ | FURIN | P09958 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5884751 | 0.95 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5884910 | 0.91 | SMN1; SMN2 (0.37) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5884729 | 0.91 | NPC1 (0.37) | SMN1; SMN2NPC1RAB9APOLBMAPK1 | |
| SCHEMBL5884773 | 0.90 | MEN1 (0.42) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5884759 | 0.89 | MEN1 (0.43) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL5884872 | 0.88 | SMN1; SMN2 (0.34) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5884473 | 0.88 | FFAR1 (0.38) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5884586 | 0.86 | SMN1; SMN2 (0.37) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5883966 | 0.86 | NPY1R (0.41) | SMN1; SMN2NPC1RAB9APOLBMAPK1 | |
| SCHEMBL5884326 | 0.86 | NPC1 (0.38) | SMN1; SMN2NPC1RAB9APOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078403-B1 | Antiviral agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2006-07-18 | — | — | US | claimed |