SCHEMBL5884803

SCHEMBL5884803

CC=CCNCCCCC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.55
ALDH1A1 P00352 1/20 0.55
KDM1A O60341 5/20 0.54
ADH1B P00325 2/20 0.44
ADH1C P00326 2/20 0.44
ADH1A P07327 2/20 0.44
ADH7 P40394 2/20 0.44
EPHX1 P07099 2/20 0.44
ADH4 P08319 1/20 0.44
S1PR2 O95136 5/20 0.36
S1PR4 O95977 5/20 0.36
S1PR1 P21453 5/20 0.36
S1PR3 Q99500 5/20 0.36
HRH4 Q9H3N8 1/20 0.36
HRH3 Q9Y5N1 1/20 0.36
S1PR5 Q9H228 1/20 0.36
SIGMAR1 Q99720 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C19 P33261 1/20 0.35
PAOX Q6QHF9 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5884796 1.00 TSHR (0.55) TSHRALDH1A1KDM1AADH1BADH1C
SCHEMBL20037699 0.98 KDM1A (0.58) TSHRALDH1A1KDM1AADH1BADH1C
SCHEMBL22157514 0.98 KDM1A (0.58) TSHRALDH1A1KDM1AADH1BADH1C
Hydrochloric Acid SCHEMBL22771742 0.98 TSHR (0.52) TSHRALDH1A1KDM1AADH1BADH1C
Hydrochloric Acid SCHEMBL22771740 0.98 TSHR (0.52) TSHRALDH1A1KDM1AADH1BADH1C
Hydrochloric Acid SCHEMBL28960716 0.96 KDM1A (0.56) TSHRALDH1A1KDM1AADH1BADH1C
SCHEMBL619431 0.93
SCHEMBL619432 0.93
Hydrochloric Acid SCHEMBL28461895 0.91 KDM1A (0.54) TSHRALDH1A1KDM1AADH1BADH1C
SCHEMBL2556426 0.85 KDM1A (0.59) TSHRALDH1A1KDM1ACYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3884019-A1 HOME CARE COMPOSITIONS Colgate-Palmolive Company (US) 2021-09-29 EP disclosed
CN-113227340-A Home care compositions 高露洁-棕榄公司 2021-08-06 CN disclosed
US-11008533-B2 Home care compositions COLGATE-PALMOLIVE COMPANY (US) 2021-05-18 US disclosed
WO-2020139335-A1 HOME CARE COMPOSITIONS COLGATE-PALMOLIVE COMPANY (US) 2020-07-02 WO disclosed
US-20200208081-A1 HOME CARE COMPOSITIONS COLGATE-PALMOLIVE COMPANY (US) 2020-07-02 US disclosed
CN-107835811-B Anilinopyrimidine derivatives and uses thereof 正大天晴药业集团股份有限公司 2019-11-08 CN disclosed
CN-106573880-B Amyloid targeting agents and methods of use thereof 阿米达斯公司 2019-07-30 CN disclosed
US-7064236-B2 Substituted 1-aryl-but-3-enylamine and 1-aryl-but-2-enylamine compounds GRUNENTHAL GMBH (DE) 2006-06-20 US disclosed