SCHEMBL5884935

SCHEMBL5884935

C=CC(=O)O[C@@H]1CO[C@H]2[C@@H]1OC[C@@H]2O

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.47
THRB P10828 1/20 0.45
LMNA P02545 1/20 0.45
BCHE P06276 11/20 0.45
JAK2 O60674 2/20 0.38
JAK1 P23458 2/20 0.38
TYK2 P29597 2/20 0.38
JAK3 P52333 2/20 0.38
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14932271 1.00 MAPT (0.47) MAPTTHRBLMNABCHEJAK2
SCHEMBL17761397 1.00 MAPT (0.47) MAPTTHRBLMNABCHEJAK2
SCHEMBL21473959 1.00 MAPT (0.47) MAPTTHRBLMNABCHEJAK2
SCHEMBL9434039 1.00 MAPT (0.47) MAPTTHRBLMNABCHEJAK2
SCHEMBL5884938 1.00 MAPT (0.47) MAPTTHRBLMNABCHEJAK2
SCHEMBL24089890 1.00 MAPT (0.47) MAPTTHRBLMNABCHEJAK2
SCHEMBL17761399 1.00 MAPT (0.47) MAPTTHRBLMNABCHEJAK2
SCHEMBL10039277 0.91 BCHE (0.43) MAPTBCHEALDH1A1
SCHEMBL13945598 0.91 BCHE (0.43) MAPTBCHEALDH1A1
SCHEMBL19216381 0.91 BCHE (0.43) MAPTBCHEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170082936-A1 Bio-Based Acrylate And Methacrylate Resins XEROX CORPORATION 2017-03-23 US claimed
US-20160139526-A1 Bio-based Acrylate and (Meth)acrylate Resins XEROX CORPORATION 2016-05-19 US claimed
CN-105198892-A Synthetic method of isosorbide acrylate and application of isosorbide acrylate in improving thermal performance of polymer NANJING UNIVERSITY OF TECHNOLOGY 2015-12-30 CN claimed
EP-0067964-B1 PROCESS FOR THE PREPARATION OF 2-ISOSORBIDE NITRATE Heinrich Mack Nachf. (DE) 1985-04-03 EP claimed
EP-0044928-B1 1,4;3,6-DIANHYDRO-HEXITE-NITRATE SUBSTITUTED BY PURINE BASES, PROCESS FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL COMPOSITIONS Dr. Willmar Schwabe GmbH & Co. (DE) 1985-03-13 EP claimed
US-4431830-A Process for the preparation of isosorbide-5-nitrate CASSELLA AKTIENGESELLSCHAFT (DE) 1984-02-14 US claimed
US-4417065-A ACYLATION OF ISOSORBIDE AND ESTERIFICATION WITH NITRIC ACID HEINRICH MACK NACHF. CHEM.-PHARMAZEUTISCHE FABRIK (DE) 1983-11-22 US claimed
US-4371703-A Process for the production of isosorbide-5-nitrate HEINRICH MACK NACHF. CHEM-PARM. FABRIK (DE) 1983-02-01 US claimed
EP-4045546-B1 METHOD FOR PRODUCING A REMOVABLE PRESSURE-SENSITIVE ADHESIVE (PSA) AND PRESSURE-SENSITIVE ADHESIVE THUS PRODUCED THE UNIV OF THE BASQUE COUNTRY (ES) 2023-11-08 EP disclosed
US-11775017-B2 Bendable displays HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2023-10-03 US disclosed
CN-113166380-B RMA crosslinkable polymers 欧尼克斯荷兰有限公司 2023-04-25 CN disclosed
US-20230104552-A1 BENDABLE DISPLAYS HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2023-04-06 US disclosed
EP-3891206-A1 RMA CROSSLINKABLE POLYMER Allnex Netherlands B.V. (NL) 2021-10-13 EP disclosed
WO-2021201877-A1 BENDABLE DISPLAYS HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2021-10-07 WO disclosed
US-4431830-A Process for the preparation of isosorbide-5-nitrate CASSELLA AKTIENGESELLSCHAFT (DE) 1984-02-14 US disclosed
US-4417065-A ACYLATION OF ISOSORBIDE AND ESTERIFICATION WITH NITRIC ACID HEINRICH MACK NACHF. CHEM.-PHARMAZEUTISCHE FABRIK (DE) 1983-11-22 US disclosed
US-4417065-A ACYLATION OF ISOSORBIDE AND ESTERIFICATION WITH NITRIC ACID HEINRICH MACK NACHF. CHEM.-PHARMAZEUTISCHE FABRIK (DE) 1983-11-22 US disclosed
US-4371703-A Process for the production of isosorbide-5-nitrate HEINRICH MACK NACHF. CHEM-PARM. FABRIK (DE) 1983-02-01 US disclosed
US-4371703-A Process for the production of isosorbide-5-nitrate HEINRICH MACK NACHF. CHEM-PARM. FABRIK (DE) 1983-02-01 US disclosed
US-4297286-A Process for selectively producing isosorbide-5-nitrate SANOL SCHWARZ-MONHEIN GMBH (DE) 1981-10-27 US disclosed