SCHEMBL5886341

SCHEMBL5886341

CCCC1CCC(c2ccc(C(=O)Oc3ccc(C#N)c(F)c3)cc2)CC1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.49
ALDH1A1 P00352 2/20 0.47
MAPT P10636 2/20 0.47
LMNA P02545 1/20 0.47
MEN1 O00255 1/20 0.42
MAPK1 P28482 1/20 0.42
KMT2A Q03164 1/20 0.42
TRPV4 Q9HBA0 1/20 0.35
TRPC3 Q13507 1/20 0.35
TRPC6 Q9Y210 1/20 0.35
GPR119 Q8TDV5 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
AOC3 Q16853 3/20 0.35
TRPA1 O75762 1/20 0.34
KDM1A O60341 3/20 0.34
FASN P49327 1/20 0.34
EGLN2 Q96KS0 2/20 0.34
NR3C2 P08235 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20152471 1.00 CYP2C9 (0.49) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL7910632 1.00 CYP2C9 (0.49) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL7908258 0.94 CYP2C9 (0.42) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL7507632 0.94 CYP2C9 (0.42) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL14300473 0.94 CYP2C9 (0.49) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL13325809 0.93 CYP2C9 (0.42) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL7514450 0.93 CYP2C9 (0.42) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL7907223 0.93 CYP2C9 (0.42) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL14526025 0.92 CYP2C9 (0.43) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL7516179 0.92 CYP2C9 (0.38) CYP2C9ALDH1A1MAPTLMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10011773-B2 Liquid crystal display device DIC CORPORATION (JP) 2018-07-03 US disclosed
US-20180171234-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2018-06-21 US disclosed
US-20180171229-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2018-06-21 US disclosed
US-20180134961-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2018-05-17 US disclosed
US-9809752-B2 Liquid crystal display device DIC CORPORATION (JP) 2017-11-07 US disclosed
US-9507185-B2 Switch element comprising a liquid crystalline medium MERCK PATENT GMBH (DE) 2016-11-29 US disclosed
US-9410086-B2 Liquid crystal-polymer composite material DIC CORPORATION (JP) 2016-08-09 US disclosed
US-9410086-B2 Liquid crystal-polymer composite material DIC CORPORATION (JP) 2016-08-09 US disclosed
US-20160215217-A1 LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2016-07-28 US disclosed
US-20160215217-A1 LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2016-07-28 US disclosed
EP-0733692-A1 Liquid crystalline compound, liquid crystal composition containing the same, and display device Chisso Corporation (JP) 1996-09-25 EP disclosed
EP-0727473-A2 Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element Chisso Corporation (JP) 1996-08-21 EP disclosed
EP-0688754-A1 DICYCLOHEXYLETHYLENE DERIVATIVE CHISSO CORPORATION (JP) 1995-12-27 EP disclosed
EP-0679707-A1 Liquid crystalline compound, liquid crystal composition and liquid crystal display element Chisso Corporation (JP) 1995-11-02 EP disclosed
EP-0673986-A2 Active matrix type liquid crystal display apparatus HITACHI, LTD. (JP) 1995-09-27 EP disclosed
US-5387369-A With specified mixture of components; short switching times MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-02-07 US disclosed
US-5030383-A With low temperature dependence of threshold voltage MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-07-09 US disclosed
US-4877547-A Liquid crystal display element MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-10-31 US disclosed
US-4853149-A STABILITY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-08-01 US disclosed
US-4818428-A MIXTURE OF POLAR AND APOLAR COMPOUNDS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-04-04 US disclosed