Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 7/20 | 0.78 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.60 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLR1A | O95602 | 3/20 | 0.48 |
| ▸ | UHRF1 | Q96T88 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.43 |
| ▸ | ECE1 | P42892 | 1/20 | 0.41 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.41 |
| ▸ | WNT1 | P04628 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26459020 | 0.89 | RAD52 (0.98) | RAD52SMARCA2AOX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5886272 | 0.88 | RAD52 (0.70) | RAD52SMARCA2AOX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7063204 | 0.87 | RAD52 (0.69) | RAD52SMARCA2AOX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5886244 | 0.86 | RAD52 (0.67) | RAD52SMARCA2AOX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5886330 | 0.84 | RAD52 (0.64) | RAD52SMARCA2AOX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL24684963 | 0.81 | RAD52 (0.76) | RAD52SMARCA2AOX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5886543 | 0.81 | RAD52 (0.61) | RAD52SMARCA2AOX1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10866187 | 0.81 | RAD52 (0.78) | RAD52SMARCA2AOX1ALDH1A1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL5886437 | 0.80 | RAD52 (0.56) | RAD52SMARCA2AOX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5886332 | 0.79 | RAD52 (0.58) | RAD52SMARCA2AOX1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132419-B2 | Pharmaceutical compounds | XENOVA LIMITED (GB) | 2006-11-07 | — | — | US | claimed |