SCHEMBL5886535

SCHEMBL5886535

CCC[C@H]1CC[C@H](CC[C@H]2CC[C@H](c3cc(F)c([N+](=O)[O-])c(F)c3)CC2)CC1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.42
ALDH1A1 P00352 4/20 0.40
MAPT P10636 3/20 0.40
LMNA P02545 1/20 0.40
MAPK1 P28482 3/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
ESR2 Q92731 1/20 0.32
PTGER4 P35408 1/20 0.31
GRIN2D O15399 1/20 0.30
GRIN3B O60391 1/20 0.30
GRIN1 Q05586 1/20 0.30
GRIN2A Q12879 1/20 0.30
GRIN2B Q13224 1/20 0.30
GRIN2C Q14957 1/20 0.30
GRIN3A Q8TCU5 1/20 0.30
THRB P10828 1/20 0.30
GPR174 Q9BXC1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5886540 1.00 CYP2C9 (0.42) CYP2C9ALDH1A1MAPTLMNAMAPK1
SCHEMBL10929444 0.99 CYP2C9 (0.43) CYP2C9ALDH1A1MAPTLMNAMAPK1
SCHEMBL10929436 0.99 CYP2C9 (0.43) CYP2C9ALDH1A1MAPTLMNAMAPK1
SCHEMBL10895765 0.95 CYP2C9 (0.40) CYP2C9ALDH1A1MAPTLMNAMAPK1
SCHEMBL10930880 0.95 CYP2C9 (0.40) CYP2C9ALDH1A1MAPTLMNAMAPK1
SCHEMBL10895750 0.95 CYP2C9 (0.40) CYP2C9ALDH1A1MAPTLMNAMAPK1
SCHEMBL10894584 0.90 CYP2C9 (0.35) CYP2C9ALDH1A1MAPTLMNAMAPK1
SCHEMBL10894589 0.90 CYP2C9 (0.35) CYP2C9ALDH1A1MAPTLMNAMAPK1
SCHEMBL10892210 0.89 MEN1 (0.37) CYP2C9ALDH1A1MAPTLMNAMAPK1
SCHEMBL10892201 0.89 MEN1 (0.37) CYP2C9ALDH1A1MAPTLMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0673986-B1 Active matrix type liquid crystal display apparatus HITACHI LTD (JP) 2003-06-04 EP claimed
EP-1070753-A2 Liquid crystal compounds and their use in active matrix type liquid crystal display devices HITACHI, LTD. (JP) 2001-01-24 EP claimed
EP-0673986-A2 Active matrix type liquid crystal display apparatus HITACHI, LTD. (JP) 1995-09-27 EP claimed
US-7112355-B2 Active matrix type liquid crystal display apparatus HITACHI LTD. (JP) 2006-09-26 US disclosed
US-20050084623-A1 Active matrix type liquid crystal display apparatus IPS ALPHA SUPPORT CO., LTD. (JP) 2005-04-21 US disclosed
US-6849309-B2 Active matrix type liquid crystal display apparatus HITACHI, LTD. (JP) 2005-02-01 US disclosed
US-6830787-B1 Active matrix liquid crystal display apparatus HITACHI, LTD. (JP) 2004-12-14 US disclosed
US-20030201422-A1 Active matrix type liquid crystal display apparatus HITACHI DISPLAYS, LTD. (JP) 2003-10-30 US disclosed
EP-0673986-B1 Active matrix type liquid crystal display apparatus HITACHI LTD (JP) 2003-06-04 EP disclosed
US-20020039162-A1 ACTIVE MATRIX TYPE LIQUID CRYSTAL DISPLAY APPARATUS OHE MASAHITO (JP) 2002-04-04 US disclosed
EP-1070753-A2 Liquid crystal compounds and their use in active matrix type liquid crystal display devices HITACHI, LTD. (JP) 2001-01-24 EP disclosed
US-6011606-A Parallel field active matrix type liquid crystal display using liquid crystal having particular electrical properties HITACHI, LTD. (JP) 2000-01-04 US disclosed