Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.63 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.63 |
| ▸ | MMP2 | P08253 | 1/20 | 0.61 |
| ▸ | MMP12 | P39900 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.56 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5886550 | 0.92 | KCNH2 (0.59) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL5886588 | 0.91 | FFAR1 (0.53) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL5036576 | 0.90 | FFAR1 (0.59) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL12348503 | 0.90 | FFAR1 (0.55) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL4280716 | 0.90 | FFAR1 (0.59) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL3685582 | 0.90 | FFAR1 (0.55) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL5886641 | 0.90 | KCNH2 (0.60) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL6719098 | 0.90 | FFAR1 (0.55) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL1897376 | 0.90 | FFAR1 (0.55) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL8391647 | 0.90 | FFAR1 (0.59) | FFAR1FFAR4MMP2MMP12KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105707-B2 | Process for preparing alkynyl-substituted aromatic and heterocyclic compounds | PHARMACORE, INC. (US) | 2006-09-12 | — | — | US | disclosed |
| US-20050137402-A1 | Process for preparing alkynyl-substituted aromatic and heterocyclic compounds | DSM N.V. (NL) | 2005-06-23 | — | — | US | disclosed |
| US-6884571-B2 | Intermediate layer composition for three-layer resist process and pattern formation method using the same | FUJI PHOTO FILM CO., LTD (JP) | 2005-04-26 | — | — | US | disclosed |
| US-20030207208-A1 | Intermediate layer composition for three-layer resist process and pattern formation method using the same | FUJI PHOTO FILM CO., LTD. | 2003-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050137402-A1 | Process for preparing alkynyl-substituted aromatic and heterocyclic compounds | NAT1, B3GNT2, NISCH | FFAR1 4642/4885FFAR4 3669/4885MMP2 4830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.