SCHEMBL58877

SCHEMBL58877

[C]1=NNOC=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5229280 0.55
SCHEMBL222064 0.48
SCHEMBL129462 0.48
SCHEMBL735951 0.40
SCHEMBL2479932 0.33
SCHEMBL56545 0.33
Cesium SCHEMBL31442422 0.33
SCHEMBL10644791 0.30
SCHEMBL7167813 0.30
SCHEMBL15522455 0.30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3094 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116437701-A Organic electroluminescent device 北京夏禾科技有限公司 2023-07-14 CN claimed
US-20230217823-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-07-06 US claimed
CN-114907280-A Organic compound and application thereof 武汉天马微电子有限公司 2022-08-16 CN claimed
WO-2022115521-A1 (HETEO)ARYL SUBSTITUTED PYRROLO-, PYRAZOLO- AND TRIAZOLOPYRIDAZINE DERIVATES AS MAT2A INHIBITORS SERVIER PHARMACEUTICALS, LLC (US) 2022-06-02 WO claimed
CN-110418790-B Imidazopyrrolone compounds as p53-MDM2 inhibitors 罗欣药业(上海)有限公司 2022-05-17 CN claimed
CN-113710675-A Fused 9-hydroxy-1, 8-dioxo-1, 3,4, 8-tetrahydro-2H-pyrido [1,2-a ] pyrazine-7-carboxamides as HIV integrase inhibitors 亚历山大·瓦西里耶维奇·伊瓦切恩科 2021-11-26 CN claimed
CN-111116577-A Fused tetracyclic compounds and application thereof in medicines 广东东阳光药业有限公司 2020-05-08 CN claimed
US-20120196852-A1 INHIBITORS OF METHIONINE AMINOPEPTIDASES AND METHODS OF TREATING DISORDERS THE JOHNS HOPKINS UNIVERSITY (US) 2012-08-02 US claimed
US-20110046146-A9 Phosphodiesterase 4 inhibitors SCHUMACHER RICHARD A 2011-02-24 US claimed
WO-2011017519-A2 INHIBITORS OF METHIONINE AMINOPEPTIDASES AND METHODS OF TREATING DISORDERS THE JOHNS HOPKINS UNIVERSITY (US) 2011-02-10 WO claimed
WO-1995013808-A1 METHOD FOR SELECTIVELY INHIBITING IL-2 SIGNAL TRANSDUCTION CELL THERAPEUTICS, INC. (US) 1995-05-26 WO claimed
WO-1995013075-A1 METHOD FOR PREVENTING TISSUE INJURY FROM HYPOXIA CELL THERAPEUTICS, INC. (US) 1995-05-18 WO claimed
WO-1995012396-A1 METHOD FOR INHIBITING INTRACELLULAR VIRAL REPLICATION CELL THERAPEUTICS, INC. (US) 1995-05-11 WO claimed
US-5385897-A 3-(3-quaternary ammonium prop-1-enyl), 7-((2-(aminothiazol-4-yl), 2-(alkoxyimino)acetamido)-3-isocephems; penicillin-resistant staphylococcus ROUSSEL-UCLAF (FR) 1995-01-31 US claimed
US-5376650-A Colorants for thermoplastic resins EASTMAN CHEMICAL COMPANY (US) 1994-12-27 US claimed
US-5304560-A Treating CNS disorders; dopamine receptor antagonist FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-04-19 US claimed
US-5254625-A Blends of a thermoplastic resin and a polymeric methine dye; molding materials; heat resistance; low volatility; nonextractable; brightness; nontoxic EASTMAN KODAK COMPANY (US) 1993-10-19 US claimed
EP-0481342-A1 Quinazoline derivatives and their preparation FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-04-22 EP claimed
EP-0478195-A1 Dihydropyridazinones, pyridazinones and related compounds as fungicides ROHM AND HAAS COMPANY (US) 1992-04-01 EP claimed
EP-0214029-B1 1-DETHIA-2-THIA CEPHALOSPORANIC-ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE AS THERAPEUTIC AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1992-03-25 EP claimed