SCHEMBL5888087

SCHEMBL5888087

CCS(=O)(=O)NC(Cc1ccc(F)cc1)C(=O)N1CCC(Cn2cncn2)(C2CCCCC2)CC1

nearest known ligand 0.62

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MC4R P32245 20/20 0.62
MC3R P41968 9/20 0.61
MC1R Q01726 7/20 0.61
MC5R P33032 9/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5888092 1.00 MC4R (0.62) MC4RMC3RMC1RMC5R
SCHEMBL5888270 1.00 MC4R (0.62) MC4RMC3RMC1RMC5R
SCHEMBL5888966 0.95 MC4R (0.59) MC4RMC3RMC1RMC5R
SCHEMBL5888320 0.95 MC4R (0.59) MC4RMC3RMC1RMC5R
SCHEMBL5888317 0.95 MC4R (0.59) MC4RMC3RMC1RMC5R
SCHEMBL5888141 0.94 MC4R (0.62) MC4RMC3RMC1RMC5R
SCHEMBL5888138 0.94 MC4R (0.62) MC4RMC3RMC1RMC5R
SCHEMBL5888152 0.94 MC4R (0.62) MC4RMC3RMC1RMC5R
SCHEMBL5888333 0.92 MC4R (0.60) MC4RMC3RMC1RMC5R
SCHEMBL6173601 0.92 MC4R (0.60) MC4RMC3RMC1RMC5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7026335-B2 Melanocortin receptor ligands THE PROCTER & GAMBLE CO. (US) 2006-04-11 US claimed
US-20050171158-A1 Melanocortin receptor ligands EBETINO FRANK H (US) 2005-08-04 US claimed
EP-1499588-A1 MELANOCORTIN RECEPTOR LIGANDS THE PROCTER & GAMBLE COMPANY (US) 2005-01-26 EP claimed
WO-2003093234-A1 MELANOCORTIN RECEPTOR LIGANDS THE PROCTER & GAMBLE COMPANY (US) 2003-11-13 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050171158-A1 Melanocortin receptor ligands MC1R, MC4R, MC5R MC4R 2/4885MC3R 4/4885MC1R 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.