Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 20/20 | 0.97 |
| ▸ | SLC6A4 | P31645 | 20/20 | 0.97 |
| ▸ | SLC6A3 | Q01959 | 15/20 | 0.97 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.97 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4634060 | 1.00 | SLC6A2 (0.97) | SLC6A2SLC6A4SLC6A3KCNH2OPRK1 | |
| SCHEMBL4780993 | 0.99 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3KCNH2OPRK1 | |
| SCHEMBL4634912 | 0.99 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3KCNH2OPRK1 | |
| Hydrochloric Acid SCHEMBL5888159 | 0.99 | SLC6A2 (0.95) | SLC6A2SLC6A4SLC6A3KCNH2OPRK1 | |
| SCHEMBL5887925 | 0.97 | SLC6A2 (0.98) | SLC6A2SLC6A4SLC6A3KCNH2OPRK1 | |
| SCHEMBL4634193 | 0.97 | SLC6A2 (0.98) | SLC6A2SLC6A4SLC6A3KCNH2OPRK1 | |
| Hydrochloric Acid SCHEMBL5888117 | 0.96 | SLC6A2 (0.95) | SLC6A2SLC6A4SLC6A3KCNH2OPRK1 | |
| SCHEMBL5887907 | 0.90 | SLC6A2 (0.80) | SLC6A2SLC6A4SLC6A3KCNH2OPRK1 | |
| SCHEMBL4515300 | 0.89 | SLC6A4 (0.78) | SLC6A2SLC6A4SLC6A3KCNH2OPRK1 | |
| SCHEMBL4515298 | 0.89 | SLC6A4 (0.78) | SLC6A2SLC6A4SLC6A3KCNH2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122683-B2 | Amides useful as monoamine re-uptake inhibitors | PFIZER INC. (US) | 2006-10-17 | — | — | US | claimed |
| US-20060111429-A1 | Substituted N-[pyrrolidin-3-yl] benzamides or naphthamides; serotonin and noradrenaline receptor antagonists; urinary incontinence; arylation of the amino pyrrolidine with a carboxylic acid or acyl halide and then deprotecting | PFIZER INC | 2006-05-25 | — | — | US | claimed |
| US-7122683-B2 | Amides useful as monoamine re-uptake inhibitors | PFIZER INC. (US) | 2006-10-17 | — | — | US | disclosed |
| US-20060111429-A1 | Substituted N-[pyrrolidin-3-yl] benzamides or naphthamides; serotonin and noradrenaline receptor antagonists; urinary incontinence; arylation of the amino pyrrolidine with a carboxylic acid or acyl halide and then deprotecting | PFIZER INC | 2006-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111429-A1 | Substituted N-[pyrrolidin-3-yl] benzamides or naphthamides; serotonin and noradrenaline receptor antagonists; urinary incontinence; arylation of the amino pyrrolidine with a carboxylic acid or acyl halide and then deprotecting | ADRB3, AOC3, HRH4 | SLC6A2 33/4885SLC6A4 49/4885SLC6A3 41/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.