Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 12/20 | 0.69 |
| ▸ | MC3R | P41968 | 1/20 | 0.69 |
| ▸ | MC1R | Q01726 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | F11 | P03951 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5888102 | 0.93 | MC4R (0.67) | MC4RMC3RMC1RALDH1A1KDM4E | |
| SCHEMBL5888103 | 0.93 | MC4R (0.67) | MC4RMC3RMC1RALDH1A1KDM4E | |
| SCHEMBL5887867 | 0.92 | MC4R (0.64) | MC4RMC3RMC1RALDH1A1KDM4E | |
| SCHEMBL5887718 | 0.89 | MC4R (0.72) | MC4RMC3RMC1RALDH1A1KDM4E | |
| SCHEMBL5887751 | 0.89 | MC4R (0.72) | MC4RMC3RMC1RALDH1A1KDM4E | |
| SCHEMBL5887882 | 0.89 | MC4R (0.72) | MC4RMC3RMC1RALDH1A1KDM4E | |
| SCHEMBL5887720 | 0.89 | MC4R (0.72) | MC4RMC3RMC1RALDH1A1KDM4E | |
| SCHEMBL5887749 | 0.89 | MC4R (0.72) | MC4RMC3RMC1RALDH1A1KDM4E | |
| SCHEMBL5888408 | 0.89 | MC4R (0.72) | MC4RMC3RMC1RALDH1A1KDM4E | |
| SCHEMBL5887836 | 0.88 | MC4R (0.70) | MC4RMC3RMC1RALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7026335-B2 | Melanocortin receptor ligands | THE PROCTER & GAMBLE CO. (US) | 2006-04-11 | — | — | US | disclosed |
| US-20050171158-A1 | Melanocortin receptor ligands | EBETINO FRANK H (US) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171158-A1 | Melanocortin receptor ligands | MC1R, MC4R, MC5R | MC4R 2/4885MC3R 4/4885MC1R 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.