Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11806029 | 0.97 | — | — | |
| SCHEMBL12942452 | 0.77 | — | — | |
| SCHEMBL7592220 | 0.72 | — | — | |
| SCHEMBL6061965 | 0.72 | — | — | |
| SCHEMBL13478406 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL10667290 | 0.70 | — | — | |
| SCHEMBL18822214 | 0.70 | — | — | |
| SCHEMBL11056121 | 0.70 | — | — | |
| SCHEMBL18520334 | 0.70 | — | — | |
| SCHEMBL4282650 | 0.70 | SLC6A2 (0.41) | SLC6A2SLC6A4BLMSLC6A3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7084192-B2 | Polylactic acid composite material and molded body | Kabushiki Kaisha Toyota Chuo Kankyusho (JP) | 2006-08-01 | — | — | US | disclosed |
| US-20040054051-A1 | Polylactic acid composite material and molded body | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 2004-03-18 | — | — | US | disclosed |