SCHEMBL5889414

SCHEMBL5889414

SCC(S)CC(S)CC(S)CC(S)CC(S)CS

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NR1I2 O75469 1/20 0.47
ALDH1A1 P00352 1/20 0.47
LMNA P02545 1/20 0.47
CYP1A2 P05177 1/20 0.47
HTT P42858 1/20 0.47
HSD17B10 Q99714 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
SLC22A6 Q4U2R8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28393759 1.00 NR1I2 (0.47) NR1I2ALDH1A1LMNACYP1A2HTT
SCHEMBL28393860 1.00 NR1I2 (0.47) NR1I2ALDH1A1LMNACYP1A2HTT
SCHEMBL28393730 1.00 NR1I2 (0.47) NR1I2ALDH1A1LMNACYP1A2HTT
SCHEMBL26695478 1.00 NR1I2 (0.47) NR1I2ALDH1A1LMNACYP1A2HTT
SCHEMBL5171976 0.96
SCHEMBL28400094 0.89 NR1I2 (0.40) NR1I2ALDH1A1LMNACYP1A2HTT
SCHEMBL28395774 0.82 NR1I2 (0.35) NR1I2ALDH1A1LMNACYP1A2HTT
SCHEMBL28888503 0.80 NR1I2 (0.33) NR1I2ALDH1A1LMNACYP1A2HTT
SCHEMBL28888880 0.80 NR1I2 (0.33) NR1I2ALDH1A1LMNACYP1A2HTT
SCHEMBL891053 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117327362-A Curable resin composition 东京应化工业株式会社 2024-01-02 CN disclosed
CN-111727402-B Functional laminate and functional lens using same 株式会社德山 2022-07-15 CN disclosed
CN-111154056-B Optical composition containing polyrotaxane 株式会社德山 2021-12-21 CN disclosed
CN-107922605-B Polyrotaxane, process for producing the same, and optical composition containing the same 株式会社德山 2020-12-11 CN disclosed
CN-111727402-A Functional laminate and functional lens using same 株式会社德山 2020-09-29 CN disclosed
CN-107207851-B Method for producing photochromic cured product 株式会社德山 2020-07-17 CN disclosed
CN-111154056-A Optical composition containing polyrotaxane 株式会社德山 2020-05-15 CN disclosed
US-7026372-B2 Enic compounds, sulfur-containing polyenic compound, sulfur-containing polythiol compound, high refractive index photocurable composition and cured product thereof MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2006-04-11 US disclosed
US-20050154073-A1 Enic compounds, sulfur-containing polyenic compound, sulfur-containing polythiol compound, high refractive index photocurable composition and cured product thereof ISHII KENJI (JP) 2005-07-14 US disclosed
US-6872333-B2 Enic compounds, sulfur-containing polyenic compound, sulfur-containing polythiol compound, high refractive index photocurable composition and cured product thereof MITSUBISHI GAS CHEMICAL COMPANY, LTD. (JP) 2005-03-29 US disclosed
US-20030195270-A1 Enic compounds, sulfur-containing polyenic compound, sulfur-containing polythiol compound, high refractive index photocurable composition and cured product thereof ISHII KENJI (JP) 2003-10-16 US disclosed