⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5565060 | 0.80 | — | — | |
| SCHEMBL16821283 | 0.71 | — | — | |
| SCHEMBL11775307 | 0.71 | — | — | |
| SCHEMBL1855995 | 0.69 | — | — | |
| SCHEMBL584838 | 0.67 | TSHR (0.37) | — | |
| SCHEMBL7088547 | 0.67 | — | — | |
| SCHEMBL2326 | 0.45 | — | — | |
| SCHEMBL34570 | 0.45 | — | — | |
| SCHEMBL25407819 | 0.41 | — | — | |
| SCHEMBL17688346 | 0.41 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11752713-B2 | Polymer composition and methods using said polymer composition to manufacture ophthalmic lens | ESSILOR INTERNATIONAL (FR) | 2023-09-12 | — | — | US | disclosed |
| US-20210072425-A1 | Polymer Composition and Methods Using Said Polymer Composition to Manufacture Ophthalmic Lens | ESSILOR INTERNATIONAL (FR) | 2021-03-11 | — | — | US | disclosed |
| EP-2488028-B1 | SUBSTITUTED PIPERIDINES THAT INCREASE P53 ACTIVITY AND THE USES THEREOF | MERCK SHARP & DOHME (US) | 2020-08-19 | — | — | EP | disclosed |
| EP-3084484-B1 | POLYMER COMPOSITION AND METHODS USING SAID POLYMER COMPOSITION TO MANUFACTURE OPHTHALMIC LENS | ESSILOR INT (FR) | 2018-03-21 | — | — | EP | disclosed |
| US-20170031059-A1 | Polymer Composition and Methods Using Said Polymer Composition to Manufacture Ophthalmic Lens | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2017-02-02 | — | — | US | disclosed |
| EP-3084484-A1 | POLYMER COMPOSITION AND METHODS USING SAID POLYMER COMPOSITION TO MANUFACTURE OPHTHALMIC LENS | Essilor International (Compagnie Générale D'Optique) (FR) | 2016-10-26 | — | — | EP | disclosed |
| EP-2880030-A1 | BRIDGED RING COMPOUNDS AS HEPATITIS C VIRUS (HCV) INHIBITORS AND PHARMACEUTICAL APPLICATIONS THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2015-06-10 | — | — | EP | disclosed |
| US-8859776-B2 | Substituted piperidines that increase p53 activity and the uses thereof | MERCK SHARP & DOHME CORP. (US) | 2014-10-14 | — | — | US | disclosed |
| WO-2014019344-A1 | BRIDGED RING COMPOUNDS AS HEPATITIS C VIRUS (HCV) INHIBITORS AND PHARMACEUTICAL APPLICATIONS THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2014-02-06 | — | — | WO | disclosed |
| US-8591943-B2 | Pyrazolo[1,5-a]pyrimidine derivatives as mTOR inhibitors | MERCK SHARP & DOHME CORP. (US) | 2013-11-26 | — | — | US | disclosed |
| WO-2009097233-A1 | IMIDAZOPYRAZINES AS PROTEIN KINASE INHIBITORS | SCHERING CORPORATION (US) | 2009-08-06 | — | — | WO | disclosed |
| US-20090170861-A1 | Pyridazinone Derivatives Useful as Glucan Synthase Inhibitors | SCHERING CORPORATION AND ALBANY MOLECULAR RESEARCH, INC. | 2009-07-02 | — | — | US | disclosed |
| EP-2035416-A1 | SUBSTITUTED PIPERIDINES THAT INCREASE P53 ACTIVITY AND THE USES THEREOF | SCHERING CORPORATION (US) | 2009-03-18 | — | — | EP | disclosed |
| WO-2009017701-A2 | ANTI-MITOTIC AGENT AND AURORA KINASE INHIBITOR COMBINATION AS ANTI-CANCER TREATMENT | SCHERING CORPORATION (US) | 2009-02-05 | — | — | WO | disclosed |
| WO-2009008913-A2 | P1-NONEPIMERIZABLE KETOAMIDE INHIBITORS OF HCV NS3 PROTEASE | SCHERING CORPORATION (US) | 2009-01-15 | — | — | WO | disclosed |
| WO-2008156614-A2 | IMIDAZOPYRAZINES AS PROTEIN KINASE INHIBITORS | SCHERING CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |
| WO-2008118332-A2 | HYDRAZIDO-PEPTIDES AS INHIBITORS OF HCV NS3-PROTEASE | SCHERING CORPORATION (US) | 2008-10-02 | — | — | WO | disclosed |
| WO-2008115381-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS GLUCAN SYNTHASE INHIBITORS | SCHERING CORPORATION (US) | 2008-09-25 | — | — | WO | disclosed |
| WO-2008005268-A1 | SUBSTITUTED PIPERIDINES THAT INCREASE P53 ACTIVITY AND THE USES THEREOF | SCHERING CORPORATION (US) | 2008-01-10 | — | — | WO | disclosed |
| US-20080004287-A1 | Substituted Piperidines that Increase P53 Activity and the Uses Thereof | SCHERING CORPORATION | 2008-01-03 | — | — | US | disclosed |