Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6250579 | 0.89 | CYP19A1 (0.53) | AKR1C1MAPTHPGDMEN1KMT2A | |
| SCHEMBL6933532 | 0.89 | AKR1C1 (0.50) | AKR1C1MAPTHPGDMEN1KMT2A | |
| SCHEMBL6250582 | 0.89 | CYP19A1 (0.53) | AKR1C1MAPTHPGDMEN1KMT2A | |
| SCHEMBL14163953 | 0.85 | AKR1C1 (0.71) | AKR1C1MAPTHPGDMEN1KMT2A | |
| SCHEMBL26200067 | 0.81 | AKR1C1 (0.63) | AKR1C1MAPTHPGDMEN1KMT2A | |
| SCHEMBL7073967 | 0.80 | AKR1C1 (0.42) | AKR1C1MAPTHPGDMEN1KMT2A | |
| SCHEMBL2962953 | 0.79 | CES1 (0.50) | AKR1C1MAPTHPGDMEN1KMT2A | |
| SCHEMBL13412380 | 0.79 | CES1 (0.50) | AKR1C1MAPTHPGDMEN1KMT2A | |
| SCHEMBL2962954 | 0.79 | CES1 (0.50) | AKR1C1MAPTHPGDMEN1KMT2A | |
| SCHEMBL28653460 | 0.79 | AKR1C1 (0.70) | AKR1C1MAPTHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2822559-A1 | IMIDAZO [1, 2 - B]PYRIDAZINE - BASED COMPOUNDS, COMPOSITIONS COMPRISING THEM, AND USES THEREOF | Lexicon Pharmaceuticals, Inc. (US) | 2015-01-14 | — | — | EP | disclosed |
| WO-2013134219-A1 | IMIDAZO [1, 2 - B] PYRIDAZINE - BASED COMPOUNDS, COMPOSITIONS COMPRISING THEM, AND USES THEREOF | LEXICON PHARMACEUTICALS, INC. (US) | 2013-09-12 | — | — | WO | disclosed |
| US-8114509-B2 | Metal oxide membrane with a gas-selective compound | EIDGENOSSISCHE TECHNISCHE HOCHSCHULE ZURICH (CH) | 2012-02-14 | — | — | US | disclosed |
| US-20090199619-A1 | Metal oxide membrane with a gas-selective compound | UNIVERSIDAD DE GRANADA (ES) | 2009-08-13 | — | — | US | disclosed |
| EP-1889050-B1 | METAL OXIDE MEMBRANE WITH A GAS-SELECTIVE COMPOUND | EIDGENOESS TECH HOCHSCHULE (CH) | 2009-02-25 | — | — | EP | disclosed |
| EP-1889050-A1 | METAL OXIDE MEMBRANE WITH A GAS-SELECTIVE COMPOUND | Eidgenössische Technische Hochschule Zürich (CH) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006119986-A1 | METAL OXIDE MEMBRANE WITH A GAS-SELECTIVE COMPOUND | EIDGENÖSSICHE TECHNISCHE HOCHSCHULE ZÜRICH (CH) | 2006-11-16 | — | — | WO | disclosed |
| EP-1722223-A1 | Metal oxide membrane with a gas-selective compound | Eidgenossisch Technische Hochschule Zürich (CH) | 2006-11-15 | — | — | EP | disclosed |