SCHEMBL589455

SCHEMBL589455

Cc1cc(C(C)(Cc2ccccc2)c2ccc(O)c(C)c2)ccc1O

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 13/20 0.59
ESR2 Q92731 7/20 0.59
AR P10275 3/20 0.50
PDE10A Q9Y233 1/20 0.41
SLC6A2 P23975 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
CYP2D6 P10635 1/20 0.40
TP53 P04637 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31717175 1.00 ESR1 (0.59) ESR1ESR2ARPDE10ASLC6A2
SCHEMBL25314566 0.86 ESR1 (0.57) ESR1ESR2ARPDE10A
SCHEMBL29499838 0.86 ESR1 (0.57) ESR1ESR2ARPDE10A
SCHEMBL30375402 0.85 ESR1 (0.56) ESR1ESR2AR
SCHEMBL2031129 0.82 SLC6A2 (0.44) ESR1ESR2SLC6A2TAAR1CYP1A2
SCHEMBL30471649 0.82 ESR1 (0.42) ESR1ESR2SLC6A2TAAR1CYP1A2
SCHEMBL17060504 0.82 ESR1 (0.50) ESR1ESR2CYP1A2CYP2C9CYP2C19
SCHEMBL2050141 0.81 ESR1 (0.57) ESR1ESR2ARPDE10ACYP1A2
SCHEMBL30374804 0.80 ESR1 (0.54) ESR1ESR2AR
SCHEMBL2417003 0.78 ESR1 (0.57) ESR1ESR2ARSLC6A2TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7671167-B2 Poly(arylene ether) copolymer SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-03-02 US claimed
US-20090247724-A1 POLY(ARYLENE ETHER) COPOLYMER SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2009-10-01 US claimed
EP-1969030-A2 POLY (ARYLENE ETHER) COPOLYMER GENERAL ELECTRIC COMPANY (US) 2008-09-17 EP claimed
EP-1966279-A1 POLYFUNCTIONAL POLY(ARYLENE ETHER) METHOD General Electric Company (US) 2008-09-10 EP claimed
WO-2007067669-A2 POLY (ARYLENE ETHER) COPOLYMER GENERAL ELECTRIC COMPANY (US) 2007-06-14 WO claimed
US-20070135609-A1 Poly(arylene ether) copolymer SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2007-06-14 US claimed
WO-2007058779-A1 POLYFUNCTIONAL POLY(ARYLENE ETHER) METHOD GENERAL ELECTRIC COMPANY (US) 2007-05-24 WO claimed
US-20070106051-A1 Polyfunctional poly(arylene ether) method CITIBANK, N.A., AS COLLATERAL AGENT 2007-05-10 US claimed
EP-3636692-B1 POLY(ARYLENE ETHER) COPOLYMER SHPP GLOBAL TECH BV (NL) 2026-04-29 EP disclosed
US-12503593-B2 Curable thermosetting composition including poly(arylene ether) copolymer SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2025-12-23 US disclosed
EP-3919545-B1 CURABLE THERMOSETTING COMPOSITION INCLUDING POLY(ARYLENE ETHER) COPOLYMER SHPP GLOBAL TECH BV (NL) 2025-10-22 EP disclosed
US-20240376240-A1 PHENYLENE ETHER OLIGOMER AND CURABLE THERMOSETTING COMPOSITION COMPRISING THE PHENYLENE ETHER OLIGOMER SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2024-11-14 US disclosed
EP-3919544-B1 POLY(ARYLENE ETHER) COPOLYMER, METHOD TO PREPARE THE SAME, AND ARTICLE DERIVED THEREFROM SHPP GLOBAL TECH BV (NL) 2024-02-07 EP disclosed
US-20230227606-A1 POLY(ARYLENE ETHER) COPOLYMER, METHOD TO PREPARE THE SAME, AND ARTICLE DERIVED THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2023-07-20 US disclosed
US-6458913-B1 DECORATIVE FILM OR SUBSTRATE, AND AN ADJACENT INJECTION MOLDED POLYMERIC BASE COMPRISING A SUBSTANTIALLY TRANSPARENT CYCLOALIPHATIC POLYESTER RESIN WHICH MAY HAVE AN OPENING FOR EXPOSING THE TRANSPARENT POLYMERIC BASE RESIN TO THE EXTERIOR GENERAL ELECTRIC COMPANY 2002-10-01 US disclosed
US-20020128357-A1 Flame retardant polycarbonate polyester composition GENERAL ELECTRIC COMPANY 2002-09-12 US disclosed
US-20020111428-A1 Transparent polycarbonate polyester composition and process GENERAL ELECTRIC COMPANY 2002-08-15 US disclosed
EP-1165689-A1 COMPOSITION AND ARTICLE FOR OPTICAL DATA STORAGE DEVICES GENERAL ELECTRIC COMPANY (US) 2002-01-02 EP disclosed
US-20010044003-A1 Composition and article for optical data storage devices GENERAL ELECTRIC CO. 2001-11-22 US disclosed
WO-2000052096-A1 COMPOSITION AND ARTICLE FOR OPTICAL DATA STORAGE DEVICES GENERAL ELECTRIC COMPANY (US) 2000-09-08 WO disclosed