Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11614422 | 0.86 | TSHR (0.47) | TSHRCYP19A1HTTKDM4ENPC1 | |
| SCHEMBL942208 | 0.86 | TSHR (0.47) | TSHRCYP19A1HTTKDM4ENPC1 | |
| SCHEMBL899185 | 0.86 | TSHR (0.47) | TSHRCYP19A1HTTKDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL11609946 | 0.84 | TSHR (0.45) | TSHRCYP19A1HTTKDM4ENPC1 | |
| SCHEMBL11615391 | 0.82 | TSHR (0.44) | TSHRCYP19A1HTTKDM4ENPC1 | |
| SCHEMBL11613442 | 0.82 | TSHR (0.44) | TSHRCYP19A1HTTKDM4ENPC1 | |
| SCHEMBL3560709 | 0.82 | HTT (0.46) | TSHRCYP19A1HTTKDM4ENPC1 | |
| SCHEMBL16515847 | 0.81 | TSHR (0.42) | TSHRCYP19A1HTTKDM4ENPC1 | |
| SCHEMBL18261884 | 0.81 | TSHR (0.42) | TSHRCYP19A1HTTKDM4ENPC1 | |
| SCHEMBL9360024 | 0.78 | TSHR (0.43) | TSHRHTTKDM4ENPC1S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106243020-A | A kind of diethylenetriamine tetrem acids paramagnetic probes for protein labeling | 南开大学 | 2016-12-21 | — | — | CN | claimed |
| CN-104610138-A | Method for synthesizing ethylenediamine tetraacetic acid type probe for protein paramagnetic labeling | UNIV NANKAI | 2015-05-13 | — | — | CN | claimed |
| EP-0397474-B1 | Photosensitive composition | TOSHIBA KK (JP) | 1997-12-10 | — | — | EP | claimed |
| EP-0397474-A2 | Photosensitive composition | KABUSHIKI KAISHA TOSHIBA (JP) | 1990-11-14 | — | — | EP | claimed |
| US-4189556-A | POLYMERIZING ALPHA-OLEFINS USING A TRANSITION METAL HALIDE-ALUMINUM ALKYL CATALYST, SUBSTITUTED PYRIDINES, QUINOLINES, OR N-OXIDE PYRIDINES | STANDARD OIL COMPANY (INDIANA) (US) | 1980-02-19 | — | — | US | claimed |
| CN-104910148-B | Aminotriazole(ATA) and pyridine and its as kinase inhibitor purposes | 西格诺药品有限公司 | 2017-06-27 | — | — | CN | disclosed |
| CN-106243020-A | A kind of diethylenetriamine tetrem acids paramagnetic probes for protein labeling | 南开大学 | 2016-12-21 | — | — | CN | disclosed |
| US-20160207930-A1 | NOVEL NEUROKININ 1 RECEPTOR ANTAGONIST COMPOUNDS II | LEO PHARMA A/S (DK) | 2016-07-21 | — | — | US | disclosed |
| EP-2344494-B1 | AMINOTRIAZOLOPYRIDINES AND THEIR USE AS KINASE INHIBITORS | SIGNAL PHARM LLC (US) | 2016-04-20 | — | — | EP | disclosed |
| CN-104910148-A | Aminotriazolopyridines and use thereof as kinase inhibitors | SIGNAL PHARM LLC | 2015-09-16 | — | — | CN | disclosed |
| CN-104610138-A | Method for synthesizing ethylenediamine tetraacetic acid type probe for protein paramagnetic labeling | UNIV NANKAI | 2015-05-13 | — | — | CN | disclosed |
| CN-102203093-B | Aminotriazolopyridines and their use as kinase inhibitors | SIGNAL PHARM LLC | 2015-05-13 | — | — | CN | disclosed |
| WO-2004026836-A2 | 1-PYRIDIN-4-YL-UREA DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2004-04-01 | — | — | WO | disclosed |
| EP-0397474-B1 | Photosensitive composition | TOSHIBA KK (JP) | 1997-12-10 | — | — | EP | disclosed |
| US-5100768-A | Photoresists for integrated circuits, polyvinyl phenol and nitrogen containing heterocycle | KABUSHIKI KAISHA TOSHIBA (JP) | 1992-03-31 | — | — | US | disclosed |
| EP-0397474-A2 | Photosensitive composition | KABUSHIKI KAISHA TOSHIBA (JP) | 1990-11-14 | — | — | EP | disclosed |
| US-4189556-A | POLYMERIZING ALPHA-OLEFINS USING A TRANSITION METAL HALIDE-ALUMINUM ALKYL CATALYST, SUBSTITUTED PYRIDINES, QUINOLINES, OR N-OXIDE PYRIDINES | STANDARD OIL COMPANY (INDIANA) (US) | 1980-02-19 | — | — | US | disclosed |
| US-4122264-A | Pyridine containing morpholines | THE UPJOHN COMPANY (US) | 1978-10-24 | — | — | US | disclosed |
| US-4115396-A | HYPOTENSIVE AGENTS | THE UPJOHN COMPANY (US) | 1978-09-19 | — | — | US | disclosed |
| US-4067874-A | Novel pyridine 1-oxides | THE UPJOHN COMPANY (US) | 1978-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160207930-A1 | NOVEL NEUROKININ 1 RECEPTOR ANTAGONIST COMPOUNDS II | TACR2, TACR1, HRH4 | TSHR 344/4885CYP19A1 2812/4885HTT 2016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.