Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1930146 | 0.89 | — | — | |
| SCHEMBL1276 | 0.89 | — | — | |
| SCHEMBL12054244 | 0.89 | — | — | |
| SCHEMBL5609754 | 0.80 | — | — | |
| SCHEMBL4636820 | 0.80 | — | — | |
| SCHEMBL8330171 | 0.80 | — | — | |
| SCHEMBL7619632 | 0.80 | — | — | |
| SCHEMBL20585948 | 0.80 | — | — | |
| Phosphine SCHEMBL15477090 | 0.80 | — | — | |
| SCHEMBL7747559 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10305040-B2 | Spiro dihydroacridine derivatives and the use thereof as materials for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2019-05-28 | — | — | US | disclosed |
| US-10205106-B2 | Polycyclic compounds | MERCK PATENT GMBH (DE) | 2019-02-12 | — | — | US | disclosed |
| US-20160204358-A1 | POLYCYCLIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2016-07-14 | — | — | US | disclosed |
| US-20140316134-A1 | SPIRO DIHYDROACRIDINE DERIVATIVES AND THE USE THEREOF AS MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-10-23 | — | — | US | disclosed |
| US-7049304-B2 | Aryl boronic acids for treating obesity | GENZYME CORPORATION (US) | 2006-05-23 | — | — | US | disclosed |
| US-20050107336-A1 | Aryl boronic acids for treating obesity | HOLMES-FARLEY STEPHEN R (US) | 2005-05-19 | — | — | US | disclosed |
| US-6858592-B2 | Aryl boronic acids for treating obesity | GENZYME CORPORATION (US) | 2005-02-22 | — | — | US | disclosed |