Methacrylic Acid

Methacrylic Acid

SCHEMBL5899274

C=C(C)C(=O)O.CC(c1ccccc1)c1cc(C(C)c2ccccc2)c(O)c(C(C)c2ccccc2)c1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.45
GABRA1 P14867 1/20 0.41
GABRB1 P18505 1/20 0.41
HPGD P15428 1/20 0.40
LMNA P02545 3/20 0.37
GAA P10253 2/20 0.37
HTT P42858 2/20 0.37
NPSR1 Q6W5P4 3/20 0.36
TSHR P16473 1/20 0.36
MCOLN3 Q8TDD5 1/20 0.36
VKORC1 Q9BQB6 1/20 0.35
TBXAS1 P24557 2/20 0.35
BRD4 O60885 1/20 0.35
BCL2 P10415 1/20 0.35
MCL1 Q07820 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
MAPT P10636 1/20 0.34
XBP1 P17861 1/20 0.34
ATM Q13315 1/20 0.34
CTRB1 P17538 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL288102 0.87 TYR (0.56) TYRGABRA1GABRB1HPGDLMNA
Methacrylic Acid SCHEMBL3989946 0.85 TYR (0.40) TYRHPGDLMNANPSR1TBXAS1
SCHEMBL15131557 0.85 TYR (0.55) TYRGABRA1GABRB1HPGDLMNA
SCHEMBL15131556 0.85 TYR (0.55) TYRGABRA1GABRB1HPGDLMNA
Methacrylic Acid SCHEMBL3376082 0.85 HPGD (0.52) TYRHPGDLMNANPSR1TBXAS1
SCHEMBL14089303 0.80 TYR (0.50) TYRGABRA1GABRB1HPGDLMNA
SCHEMBL312340 0.79 TYR (0.46) TYRGABRA1GABRB1HPGDGAA
SCHEMBL8425731 0.78 TYR (0.45) TYRHPGDGAAHTTNPSR1
SCHEMBL11759875 0.78 TYR (0.45) TYRGABRA1GABRB1HPGDGAA
SCHEMBL11759869 0.78 TYR (0.45) TYRGABRA1GABRB1HPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6991884-B2 Chemically prepared toner and process therefor LEXMARK INTERNATIONAL, INC. (US) 2006-01-31 US disclosed
WO-2005080282-A1 COLOR PIGMENT INKS FOR GENERAL USE LEXMARK INTERNATIONAL, INC (US) 2005-09-01 WO disclosed
US-20040137348-A1 Chemically prepared toner and process therefor LEXMARK INTERNATIONAL, INC. 2004-07-15 US disclosed