⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL384339 | 0.71 | — | — | |
| SCHEMBL1494388 | 0.71 | — | — | |
| SCHEMBL29253124 | 0.67 | — | — | |
| SCHEMBL28301689 | 0.67 | — | — | |
| SCHEMBL28300349 | 0.67 | — | — | |
| SCHEMBL30335454 | 0.67 | — | — | |
| SCHEMBL29877766 | 0.67 | — | — | |
| SCHEMBL11655766 | 0.67 | — | — | |
| SCHEMBL14829789 | 0.67 | — | — | |
| SCHEMBL5558278 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986215-A | 2-Phenyl-4-acyl benzofurans, preparation and application thereof | 中国医学科学院药物研究所 | 2024-05-07 | — | — | CN | claimed |
| EP-2081928-B1 | Pyrrolo-pyridine kinase inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2014-02-26 | — | — | EP | claimed |
| US-8114874-B2 | Substituted acetylenic imidazo[1,2-B]pyridazine compounds as kinase inhibitors | ARIAD PHARMACEUTICALS, INC. (US) | 2012-02-14 | — | — | US | claimed |
| US-20080300237-A1 | Pharmaceutically Active Diazepanes | OBERHAUSER BERNDT | 2008-12-04 | — | — | US | claimed |
| US-20030050418-A1 | Use of silicone compositions crosslinkable by the cationic route under UV radiation and of a photoinitiator of the onium borate type for coatings for sheet gaskets, in particular cylinder head gaskets | COTTING MARIE-CHRISTINE (FR) | 2003-03-13 | — | — | US | claimed |
| US-6020364-A | DOPAMINE RECEPTORS ANTAGONIST | WARNER-LAMBERT COMPANY (US) | 2000-02-01 | — | — | US | claimed |
| EP-0223177-B1 | CARDIOTONIC PHENYL OXAZOLONES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-08-19 | — | — | EP | claimed |
| EP-0315902-B1 | BIS-INDOLYL ETHYLENE ALDEHYDES | BAYER AG (DE) | 1992-03-18 | — | — | EP | claimed |
| EP-0115405-B1 | PROCESS FOR THE PREPARATION OF BETA-LACTAM COMPOUNDS | BEECHAM GROUP PLC (GB) | 1987-06-10 | — | — | EP | claimed |
| US-4435405-A | 2-(AMINOALKYLTHIO) SUBSTITUTED | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-03-06 | — | — | US | claimed |
| EP-0017396-B1 | HEPTENO-NITRILES, PROCESS FOR THEIR PREPARATION AND PERFUMERY COMPOSITIONS CONTAINING THEM | BUSH BOAKE ALLEN Limited (GB) | 1983-06-01 | — | — | EP | claimed |
| US-3978121-A | 5H Dibenzo[a,d]cycloheptene derivatives | MERCK & CO., INC. (US) | 1976-08-31 | — | — | US | claimed |
| CN-117986215-A | 2-Phenyl-4-acyl benzofurans, preparation and application thereof | 中国医学科学院药物研究所 | 2024-05-07 | — | — | CN | disclosed |
| US-10041937-B2 | Macrophage identification agent, and identification method, sorting method, evaluation method, screening method and kit using the macrophage identifier agent | CANON KABUSHIKI KAISHA (JP) | 2018-08-07 | — | — | US | disclosed |
| US-20160018389-A1 | MACROPHAGE IDENTIFICATION AGENT, AND IDENTIFICATION METHOD, SORTING METHOD, EVALUATION METHOD, SCREENING METHOD AND KIT USING THE MACROPHAGE IDENTIFIER AGENT | CANON KABUSHIKI KAISHA (JP) | 2016-01-21 | — | — | US | disclosed |
| US-8575197-B2 | Pyrolinone derivative and pharmaceutical composition comprising the same | SHIONOGI & CO., LTD. (JP) | 2013-11-05 | — | — | US | disclosed |
| US-4803157-A | Hydrolyzable fluorescent substrates for phosphatases and analytical use thereof | EASTMAN KODAK COMPANY (US) | 1989-02-07 | — | — | US | disclosed |
| EP-0104691-B1 | FUNGICIDALLY ACTIVE COMPOUNDS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-07-06 | — | — | EP | disclosed |
| US-4677210-A | 1-arylalkoxy- and 1-arylalkylthioaryl-2-pyrazolines as anti-inflammatory or anti-allergic agents | RORER PHARMACEUTICAL CORPORATION (US) | 1987-06-30 | — | — | US | disclosed |
| US-4395264-A | PRECIPITATION OF BETA-NAPHTHOL | BASF WYANDOTTE CORPORATION (US) | 1983-07-26 | — | — | US | disclosed |