Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.59 |
| ▸ | CNR1 | P21554 | 4/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.47 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | MARS1 | P56192 | 1/20 | 0.43 |
| ▸ | RPA1 | P27694 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5902998 | 0.90 | CNR2 (0.57) | CNR2CNR1HDAC3HDAC4HDAC1 | |
| SCHEMBL8369248 | 0.90 | CNR2 (0.50) | CNR2CNR1HDAC3HDAC4HDAC1 | |
| Hydrochloric Acid SCHEMBL8369717 | 0.89 | CNR2 (0.56) | CNR2CNR1HDAC3HDAC4HDAC1 | |
| SCHEMBL8313106 | 0.89 | CNR2 (0.56) | CNR2CNR1HDAC3HDAC4HDAC1 | |
| SCHEMBL8369218 | 0.88 | RPA1 (0.51) | CNR2CNR1HDAC3HDAC4HDAC1 | |
| SCHEMBL8368110 | 0.88 | CNR2 (0.49) | CNR2CNR1HDAC3HDAC4HDAC1 | |
| SCHEMBL5902441 | 0.87 | CNR2 (0.57) | CNR2CNR1HDAC3HDAC4HDAC1 | |
| SCHEMBL27436131 | 0.86 | CNR2 (0.47) | CNR2CNR1HDAC3HDAC4HDAC1 | |
| SCHEMBL8369089 | 0.83 | CNR2 (0.44) | CNR2CNR1MALT1MGLLMARS1 | |
| SCHEMBL8369627 | 0.82 | CNR2 (0.44) | CNR2CNR1HDAC6MARS1RPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060172019-A1 | Cannabinoid receptor inverse agonists and neutral antagonists as therapeutic agents for the treatment of bone disorders | ABERDEEN, THE UNIVERSITY COURT OF THE UNIVERSITY OF (GB) | 2006-08-03 | — | — | US | disclosed |
| EP-1606019-A1 | CANNABINOID RECEPTOR INVERSE AGONISTS AND NEUTRAL ANTAGONISTS AS THERAPEUTIC AGENTS FOR THE TREATMENT OF BONE DISORDERS | The University Court of The University of Aberdeen (GB) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004078261-A1 | CANNABINOID RECEPTOR INVERSE AGONISTS AND NEUTRAL ANTAGONISTS AS THERAPEUTIC AGENTS FOR THE TREATMENT OF BONE DISORDERS | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2004-09-16 | — | — | WO | disclosed |
| WO-2004078261-A1 | CANNABINOID RECEPTOR INVERSE AGONISTS AND NEUTRAL ANTAGONISTS AS THERAPEUTIC AGENTS FOR THE TREATMENT OF BONE DISORDERS | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2004-09-16 | — | — | WO | disclosed |
| US-5925768-A | ANTIINFLAMMATORY AGENTS; ANALGESICS, ANTICOAGULANTS, NARCOTICS | SANOFI (FR) | 1999-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060172019-A1 | Cannabinoid receptor inverse agonists and neutral antagonists as therapeutic agents for the treatment of bone disorders | CNR2, CNR1, GPER1 | CNR2 1/4885CNR1 2/4885HDAC3 509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.