Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 19/20 | 0.77 |
| ▸ | HRH1 | P35367 | 4/20 | 0.77 |
| ▸ | BACE1 | P56817 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5904114 | 0.99 | HRH3 (0.75) | HRH3HRH1BACE1 | |
| Hydrochloric Acid SCHEMBL5904246 | 0.98 | HRH3 (0.73) | HRH3HRH1BACE1 | |
| SCHEMBL5904192 | 0.95 | HRH3 (0.69) | HRH3HRH1BACE1 | |
| SCHEMBL5904187 | 0.94 | HRH3 (0.77) | HRH3HRH1 | |
| Hydrochloric Acid SCHEMBL5904064 | 0.93 | HRH3 (0.74) | HRH3HRH1BACE1 | |
| SCHEMBL5904130 | 0.93 | HRH3 (0.74) | HRH3HRH1BACE1 | |
| SCHEMBL5904125 | 0.92 | HRH3 (0.66) | HRH3HRH1 | |
| Hydrochloric Acid SCHEMBL5904181 | 0.92 | HRH3 (0.66) | HRH3HRH1 | |
| SCHEMBL5904091 | 0.92 | HRH3 (0.67) | HRH3HRH1BACE1 | |
| Hydrochloric Acid SCHEMBL5904180 | 0.91 | HRH3 (0.65) | HRH3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006046131-A1 | TETRALIN HISTAMINE-3 RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2006-05-04 | — | — | WO | claimed |
| US-20060094719-A1 | Tetralin histamine-3 receptor antagonists | PFIZER INC | 2006-05-04 | — | — | US | claimed |
| WO-2006046131-A1 | TETRALIN HISTAMINE-3 RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2006-05-04 | — | — | WO | disclosed |
| US-20060094719-A1 | Tetralin histamine-3 receptor antagonists | PFIZER INC | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094719-A1 | Tetralin histamine-3 receptor antagonists | HRH3, HRH4, HRH1 | HRH3 1/4885HRH1 3/4885BACE1 455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.