Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 20/20 | 0.56 |
| ▸ | PPARA | Q07869 | 6/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5904685 | 0.87 | PPARD (0.51) | PPARDPPARAPPARG | |
| SCHEMBL3964303 | 0.80 | PPARD (0.58) | PPARDPPARAPPARG | |
| SCHEMBL3961089 | 0.80 | PPARD (0.57) | PPARDPPARAPPARG | |
| SCHEMBL5904662 | 0.79 | PTGDR2 (0.44) | PPARDPPARA | |
| SCHEMBL4950397 | 0.79 | PPARD (0.56) | PPARDPPARAPPARG | |
| SCHEMBL5904796 | 0.77 | PPARD (0.62) | PPARDPPARAPPARG | |
| SCHEMBL5004906 | 0.76 | PPARD (0.61) | PPARDPPARAPPARG | |
| SCHEMBL22324044 | 0.76 | PPARD (0.65) | PPARDPPARAPPARG | |
| SCHEMBL4836042 | 0.75 | PPARD (0.76) | PPARDPPARAPPARG | |
| SCHEMBL5904809 | 0.75 | PPARD (0.59) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060241157-A1 | Heterocyclic ppar modulators | ELI LILLY AND COMPANY | 2006-10-26 | — | — | US | disclosed |
| EP-1585733-A1 | HETEROCYCLIC PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-10-19 | — | — | EP | disclosed |
| WO-2004063166-A1 | HETEROCYCLIC PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2004-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241157-A1 | Heterocyclic ppar modulators | PPARA, PPARG, PPARD | PPARD 3/4885PPARA 1/4885PPARG 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.