Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 7/20 | 0.53 |
| ▸ | ITGA4 | P13612 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | CPA1 | P15085 | 2/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5906881 | 1.00 | ITGB1 (0.53) | ITGB1ITGA4ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL5906602 | 0.93 | MME (0.50) | ITGB1ITGA4ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL5906604 | 0.93 | MME (0.50) | ITGB1ITGA4ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL5906841 | 0.89 | TACR3 (0.47) | ITGB1ITGA4ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL5906837 | 0.89 | TACR3 (0.47) | ITGB1ITGA4ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL5906814 | 0.88 | PPARG (0.51) | ITGB1ITGA4ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL5906808 | 0.88 | PPARG (0.51) | ITGB1ITGA4ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL5906948 | 0.88 | CYP1A2 (0.53) | ITGB1ITGA4ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL5906943 | 0.88 | CYP1A2 (0.53) | ITGB1ITGA4ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL5906804 | 0.88 | PPARG (0.53) | ITGB1ITGA4PTGDRMMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060089371-A1 | Phenyl or heteroaryl amino alkane derivatives as ip receptor antagonist | BAYER HEALTHCARE AG (DE) | 2006-04-27 | — | — | US | disclosed |
| CN-1735598-A | Phenyl or heteroaryl amino alkane derivatives as IP receptor antagonist | BAYER HEALTHCARE AG (DE) | 2006-02-15 | — | — | CN | disclosed |
| EP-1575919-A1 | PHENYL OR HETEROARYL AMINO ALKANE DERIVATIVES AS IP RECEPTOR ANTAGONIST | Bayer HealthCare AG (DE) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004043926-A1 | PHENYL OR HETEROARYL AMINO ALKANE DERIVATIVES AS IP RECEPTOR ANTAGONIST | BAYER HEALTHCARE AG (DE) | 2004-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060089371-A1 | Phenyl or heteroaryl amino alkane derivatives as ip receptor antagonist | BPHL, HRH4, HRH2 | ITGB1 1017/4885ITGA4 347/4885ALDH1A1 655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.