Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 2/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | SHBG | P04278 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GUSB | P08236 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9117103 | 0.79 | SRD5A1 (0.42) | SRD5A1SRD5A2SMN1; SMN2SHBGCYP2C19 | |
| SCHEMBL7529519 | 0.79 | CYP19A1 (0.58) | SRD5A1SHBGCYP19A1LMNASERPINA6 | |
| SCHEMBL3797856 | 0.79 | CYP19A1 (0.58) | SRD5A1SHBGCYP19A1LMNASERPINA6 | |
| SCHEMBL7617295 | 0.79 | SRD5A1 (0.64) | SRD5A1SHBGCYP19A1LMNASERPINA6 | |
| SCHEMBL7617290 | 0.79 | SRD5A1 (0.64) | SRD5A1SHBGCYP19A1LMNASERPINA6 | |
| SCHEMBL4421313 | 0.78 | SRD5A1 (0.58) | SRD5A1SRD5A2SHBGLMNASERPINA6 | |
| SCHEMBL12423999 | 0.78 | SRD5A1 (0.58) | SRD5A1SRD5A2SHBGLMNASERPINA6 | |
| SCHEMBL13603460 | 0.78 | SRD5A1 (0.58) | SRD5A1SRD5A2SHBGLMNASERPINA6 | |
| SCHEMBL14359642 | 0.78 | SRD5A1 (0.58) | SRD5A1SRD5A2SHBGLMNASERPINA6 | |
| SCHEMBL14185033 | 0.78 | SRD5A1 (0.58) | SRD5A1SRD5A2SHBGLMNASERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060046994-A1 | Process for preparing 3-oxo-4-aza-5-alpha-androstane-17-carboxylic acid | DR. REDDY'S LABORATORIES, INC. | 2006-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060046994-A1 | Process for preparing 3-oxo-4-aza-5-alpha-androstane-17-carboxylic acid | CYP17A1, CYP21A2, SRD5A2 | SRD5A1 8/4885SRD5A2 3/4885SMN1; SMN2 4177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.