SCHEMBL5907014

SCHEMBL5907014

COCCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OC1CCOC1

nearest known ligand 0.72

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
EGFR P00533 19/20 0.72
ERBB2 P04626 2/20 0.68
EPHA2 P29317 1/20 0.68
KDR P35968 1/20 0.68
EPHB4 P54760 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL175372 0.95 EGFR (0.73) EGFRERBB2KDREPHB4
SCHEMBL29623683 0.95 EGFR (0.73) EGFRERBB2KDREPHB4
SCHEMBL4523013 0.92 EGFR (0.77) EGFRERBB2EPHA2KDREPHB4
SCHEMBL13606791 0.92 EGFR (0.77) EGFRERBB2EPHA2KDREPHB4
SCHEMBL4523002 0.92 EGFR (0.77) EGFRERBB2EPHA2KDREPHB4
SCHEMBL4524312 0.92 EGFR (0.77) EGFRERBB2EPHA2KDREPHB4
SCHEMBL13606789 0.92 EGFR (0.77) EGFRERBB2EPHA2KDREPHB4
SCHEMBL7223380 0.91 EGFR (0.68) EGFRERBB2EPHA2KDREPHB4
SCHEMBL5228818 0.91 EGFR (0.68) EGFRERBB2EPHA2KDREPHB4
SCHEMBL7225021 0.91 EGFR (0.68) EGFRERBB2EPHA2KDREPHB4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8662076-B2 Two-part capsule with pre-closure for housing pharmaceutical preparations for powder inhalers BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2014-03-04 US disclosed
US-20060157054-A1 Two-part capsule with pre-closure for housing pharmaceutical preparations for powder inhalers BOEHRINGER LNGELHEIM PHARMA GMBH & CO. KG (DE) 2006-07-20 US disclosed