Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.54 |
| ▸ | HRH1 | P35367 | 4/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5793700 | 1.00 | HRH3 (0.64) | HRH3SIGMAR1SLC6A3HRH1SLC6A2 | |
| SCHEMBL5793108 | 0.89 | HRH3 (0.58) | HRH3SIGMAR1HRH1HTR2C | |
| SCHEMBL5793105 | 0.89 | HRH3 (0.58) | HRH3SIGMAR1HRH1HTR2C | |
| SCHEMBL5796114 | 0.89 | HRH3 (0.58) | HRH3SIGMAR1HRH1HTR2C | |
| SCHEMBL5793110 | 0.89 | HRH3 (0.58) | HRH3SIGMAR1HRH1HTR2C | |
| SCHEMBL5794553 | 0.85 | HRH3 (0.53) | HRH3SIGMAR1KCNH2HTR2C | |
| SCHEMBL5908108 | 0.84 | HRH3 (0.46) | HRH3SIGMAR1HRH1KCNH2HTR2C | |
| SCHEMBL5908112 | 0.84 | HRH3 (0.46) | HRH3SIGMAR1HRH1KCNH2HTR2C | |
| SCHEMBL5908114 | 0.84 | HRH3 (0.46) | HRH3SIGMAR1HRH1KCNH2HTR2C | |
| SCHEMBL5796731 | 0.82 | HRH3 (0.54) | HRH3HRH1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060047114-A1 | Azabicyclic amine histamine-3 receptor antagonists | PFIZER INC | 2006-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060047114-A1 | Azabicyclic amine histamine-3 receptor antagonists | HRH3, HRH4, HRH2 | HRH3 1/4885SIGMAR1 1354/4885SLC6A3 47/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.