Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 17/20 | 0.57 |
| ▸ | CHKA | P35790 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5805279 | 1.00 | HRH3 (0.57) | HRH3CHKAACHERAD52 | |
| SCHEMBL5805281 | 1.00 | HRH3 (0.57) | HRH3CHKAACHERAD52 | |
| SCHEMBL5796894 | 0.97 | HRH3 (0.55) | HRH3ACHERAD52 | |
| SCHEMBL5796893 | 0.97 | HRH3 (0.55) | HRH3ACHERAD52 | |
| SCHEMBL5796896 | 0.97 | HRH3 (0.55) | HRH3ACHERAD52 | |
| SCHEMBL5796741 | 0.88 | HRH3 (0.54) | HRH3CHKAACHERAD52 | |
| SCHEMBL5796731 | 0.88 | HRH3 (0.54) | HRH3CHKAACHERAD52 | |
| SCHEMBL5796735 | 0.88 | HRH3 (0.54) | HRH3CHKAACHERAD52 | |
| SCHEMBL5795639 | 0.86 | HRH3 (0.59) | HRH3ACHERAD52 | |
| SCHEMBL5795634 | 0.86 | HRH3 (0.59) | HRH3ACHERAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060047114-A1 | Azabicyclic amine histamine-3 receptor antagonists | PFIZER INC | 2006-03-02 | — | — | US | claimed |
| US-20060047114-A1 | Azabicyclic amine histamine-3 receptor antagonists | PFIZER INC | 2006-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060047114-A1 | Azabicyclic amine histamine-3 receptor antagonists | HRH3, HRH4, HRH2 | HRH3 1/4885CHKA 807/4885ACHE 227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.