SCHEMBL5909124

SCHEMBL5909124

CNC1CC(NC)CC(NC)C1

nearest known ligand 0.30

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 4/20 0.30
CHRNB4 P30926 4/20 0.30
CHRNA3 P32297 4/20 0.30
CHRNA7 P36544 4/20 0.30
CHRNA4 P43681 4/20 0.30
CHRNA1 P02708 3/20 0.30
CHRNG P07510 3/20 0.30
CHRNB1 P11230 3/20 0.30
CHRND Q07001 3/20 0.30
LMNA P02545 1/20 0.30
CYP3A4 P08684 1/20 0.30
PKM P14618 1/20 0.30
NFKB1 P19838 1/20 0.30
CYP2C19 P33261 1/20 0.30
THPO P40225 1/20 0.30
CHRNE Q04844 1/20 0.30
CHRNA2 Q15822 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13861306 1.00
SCHEMBL26973008 1.00
Bromide SCHEMBL6847337 0.96
SCHEMBL31483450 0.86
SCHEMBL13866433 0.84
SCHEMBL14671382 0.84
SCHEMBL22276138 0.83
SCHEMBL22536323 0.83
SCHEMBL13601390 0.81
SCHEMBL12354649 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037641-B2 Modified nucleotide reagents PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2024-07-16 US disclosed
US-20230366018-A1 LABELED NUCLEOTIDE ANALOGS, REACTION MIXTURES, AND METHODS AND SYSTEMS FOR SEQUENCING PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2023-11-16 US disclosed
US-20230366018-A1 LABELED NUCLEOTIDE ANALOGS, REACTION MIXTURES, AND METHODS AND SYSTEMS FOR SEQUENCING PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2023-11-16 US disclosed
EP-4219506-A1 PROTECTED DYE-LABELED REAGENTS Pacific Biosciences Of California, Inc. (US) 2023-08-02 EP disclosed
US-20230192749-A1 PROTECTED FLUORESCENT REAGENT COMPOUNDS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2023-06-22 US disclosed
US-20230192749-A1 PROTECTED FLUORESCENT REAGENT COMPOUNDS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2023-06-22 US disclosed
US-11578093-B2 Protected fluorescent reagent compounds PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2023-02-14 US disclosed
US-20220396702-A1 PROTECTED DYE-LABELED REAGENTS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2022-12-15 US disclosed
US-11466319-B2 Labeled nucleotide analogs, reaction mixtures, and methods and systems for sequencing PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2022-10-11 US disclosed
EP-3030683-B1 PROTECTED FLUORESCENT REAGENT COMPOUNDS PACIFIC BIOSCIENCES CALIFORNIA INC (US) 2022-03-02 EP disclosed
WO-2016126941-A1 MULTIMERIC PROTECTED FLUORESCENT REAGENTS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2016-08-11 WO disclosed
US-20150050659-A1 PROTECTED FLUORESCENT REAGENT COMPOUNDS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 2015-02-19 US disclosed
US-20150050659-A1 PROTECTED FLUORESCENT REAGENT COMPOUNDS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 2015-02-19 US disclosed
WO-2015021079-A1 PROTECTED FLUORESCENT REAGENT COMPOUNDS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2015-02-12 WO disclosed
US-20060189774-A1 Modifiable polyunsaturated polymers and processes for their preparation AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH 2006-08-24 US disclosed
US-6765104-B1 Transition metal complexes of n, n',n″trialkyl-cis-1,3,5-triaminocyclohexane and related compositions and methods of synthesis and use THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES 2004-07-20 US disclosed
WO-2001010870-A1 TRANSITION METAL COMPLEXES OF N,N',N'-TRIALKYL- CIS,CIS-1,3,5-TRIAMINOCYCLOHEXANE AND RELATED COMPOSITIONS AND METHODS OF SYNTHESIS AND USE THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2001-02-15 WO disclosed
EP-0167908-B1 BRANCHED, THERMOPLASTICALLY PROCESSABLE, IMPACT-RESISTANT POLYAMIDES BAYER AG (DE) 1990-04-04 EP disclosed
US-4611034-A POLYETHERAMIDES FROM AN AMMONIA-AMINATED POLYETHER AND A LACTAM; IMPACT STRENGTH; COLD RESISTANCE; MOLDINGS BAYER AKTIENGESELLSCHAFT (DE) 1986-09-09 US disclosed
EP-0167908-A2 Branched, thermoplastically processable, impact-resistant polyamides BAYER AG (DE) 1986-01-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150050659-A1 PROTECTED FLUORESCENT REAGENT COMPOUNDS ERCC4, ERCC2, ERCC1 CHRNB2 4219/4885CHRNB4 4446/4885CHRNA3 4704/4885
US-12037641-B2 Modified nucleotide reagents POLL, POLN, POLM CHRNB2 2409/4885CHRNB4 2138/4885CHRNA3 2702/4885
US-20220396702-A1 PROTECTED DYE-LABELED REAGENTS POLL, POLB, POLM CHRNB2 2322/4885CHRNB4 2216/4885CHRNA3 2910/4885
US-11578093-B2 Protected fluorescent reagent compounds ERCC4, ERCC2, ERCC1 CHRNB2 4219/4885CHRNB4 4446/4885CHRNA3 4704/4885
US-20230192749-A1 PROTECTED FLUORESCENT REAGENT COMPOUNDS ERCC4, ERCC2, ERCC1 CHRNB2 4219/4885CHRNB4 4446/4885CHRNA3 4704/4885
US-11466319-B2 Labeled nucleotide analogs, reaction mixtures, and methods and systems for sequencing POLL, POLN, POLB CHRNB2 1778/4885CHRNB4 1570/4885CHRNA3 1944/4885
US-20230366018-A1 LABELED NUCLEOTIDE ANALOGS, REACTION MIXTURES, AND METHODS AND SYSTEMS FOR SEQUENCING POLL, POLN, POLB CHRNB2 1778/4885CHRNB4 1570/4885CHRNA3 1944/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.