SCHEMBL59122

SCHEMBL59122

C1CNCCOC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1635363 1.00
SCHEMBL26751260 1.00 MEN1 (0.69)
SCHEMBL11602747 0.97 KDM4E (0.75)
Water SCHEMBL29126248 0.97
Hydrochloric Acid SCHEMBL58640 0.97
Piperazine SCHEMBL3367356 0.97 KDM4E (0.75)
SCHEMBL12009416 0.97 MEN1 (0.75)
SCHEMBL26751258 0.94 KDM4E (0.71)
SCHEMBL19180206 0.93
SCHEMBL624587 0.93

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 12587 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630548-B2 Azetidine derivatives for the treatment of integrin associated diseases THE UNIVERSITY OF NOTTINGHAM (GB) 2026-05-19 US claimed
EP-4041730-B1 SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS BRISTOL MYERS SQUIBB CO (US) 2026-05-13 EP claimed
EP-4731223-A1 MORPHOLINE AND 1,4-OXAZEPANE COMPOUNDS AND ITS USE IN THERAPY Universitat De Barcelona (ES) 2026-04-29 EP claimed
US-20260070896-A1 HETEROCYCLE DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS UNIV LEUVEN KATH (BE) 2026-03-12 US claimed
US-12539305-B2 Methods of treating cancer with an mTOR inhibitor Revolution Medicines, Inc. (US) 2026-02-03 US claimed
US-20260014124-A1 USE OF MTOR INHIBITORS FOR PREVENTION OF INTESTINAL POLYP GROWTH AND CANCER UNIV TEXAS (US) 2026-01-15 US claimed
US-20250388543-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN VERTEX PHARMACEUTICALS INCORPORATED (US) 2025-12-25 US claimed
US-12496296-B2 Benzodioxane modulators of leukotriene A4 hydrolase (LTA4H) for prevention and treatment of aging-associated diseases ALKAHEST, INC. (US) 2025-12-16 US claimed
US-20250376468-A1 PYRAZOLO[1,5-a]PYRIDINE DERIVATIVES FOR TREATING TRPM3-MEDIATED DISORDERS UNIV LEUVEN KATH (BE) 2025-12-11 US claimed
US-20250376469-A1 INDOLIZINE DERIVATIVES FOR TREATING TRPM3-MEDIATED DISORDERS UNIV LEUVEN KATH (BE) 2025-12-11 US claimed
US-4680358-A Styryl terminated macromolecular monomers of polyethers THE B F GOODRICH COMPANY (US) 1987-07-14 US claimed
EP-0221551-A2 Styryl terminated macromolecular monomers of polyethers The B.F. GOODRICH Company (US) 1987-05-13 EP claimed
EP-0218079-A2 Allyl terminated macromolecular monomers of polyethers The B.F. GOODRICH Company (US) 1987-04-15 EP claimed
EP-0013749-B1 HEXAHYDRO-1,4-OXAZEPINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM BASF Aktiengesellschaft (DE) 1982-05-12 EP claimed
EP-0045631-A2 Synthesis of dioxabicyclo(3.2.1)octanes and oxepanes ORTHO PHARMACEUTICAL CORPORATION (US) 1982-02-10 EP claimed
EP-0038696-A2 Synthesis of dioxabicyclo(3.2.1.)octanes and oxepanes ORTHO PHARMACEUTICAL CORPORATION (US) 1981-10-28 EP claimed
US-4276216-A Synthesis of dioxabicyclo[3.2.1]octanes and oxepanes ORTHO PHARMACEUTICAL CORPORATION (US) 1981-06-30 US claimed
US-4269833-A 7-/3-HYDROXY-, OXY-, OR CARBONYLOXY-SUBSTITUTED/PHENYL DERIVATIVES; ANALGESICS BASF AKTIENGESELLSCHAFT (DE) 1981-05-26 US claimed
EP-0013749-A1 Hexahydro-1,4-oxazepines, process for their preparation and pharmaceutical compositions containing them BASF Aktiengesellschaft (DE) 1980-08-06 EP claimed
US-4182717-A Total synthesis of the utero-evacuant substance d,l-zoapatanol ORTHO PHARMACEUTICAL CORP. (US) 1980-01-08 US claimed