SCHEMBL59138

SCHEMBL59138

c1cc(C2CCCCC2)ccc1-c1ccc(C2CCCCC2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 3/20 0.55
KMT2A Q03164 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
HSP90AA1 P07900 1/20 0.55
GAA P10253 1/20 0.55
MAPT P10636 1/20 0.55
GALR1 P47211 1/20 0.50
S1PR1 P21453 2/20 0.47
HTT P42858 2/20 0.47
LMNA P02545 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
CYP11B2 P19099 1/20 0.45
EPHX2 P34913 1/20 0.44
HAO1 Q9UJM8 1/20 0.44
ESR2 Q92731 1/20 0.43
S1PR5 Q9H228 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28451253 0.97 NOTUM (0.53) NOTUMKMT2ATDP1HSP90AA1GAA
Hydrogen Peroxide SCHEMBL28451101 0.95 NPC1 (0.52) NOTUMKMT2ATDP1HSP90AA1GAA
Hydrogen Peroxide SCHEMBL28460755 0.92 NPC1 (0.53) NOTUMKMT2ATDP1HSP90AA1GAA
SCHEMBL6275125 0.91 HDAC8 (0.52) NOTUMKMT2ATDP1HSP90AA1GAA
SCHEMBL15260520 0.91 HDAC8 (0.52) NOTUMKMT2ATDP1HSP90AA1GAA
SCHEMBL28584923 0.91 HDAC8 (0.52) NOTUMKMT2ATDP1HSP90AA1GAA
SCHEMBL42782 0.91 HDAC8 (0.52) NOTUMKMT2ATDP1HSP90AA1GAA
SCHEMBL537001 0.91 NPC1 (0.58) NOTUMKMT2ATDP1HSP90AA1GAA
SCHEMBL18561699 0.91 NPC1 (0.58) NOTUMKMT2ATDP1HSP90AA1GAA
SCHEMBL15906653 0.89 NOTUM (0.47) NOTUMKMT2ATDP1HSP90AA1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 943 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118879339-A Wide-temperature-range liquid crystal material and preparation method and application thereof 北京大学 2024-11-01 CN claimed
US-11814563-B2 Bioreachable chiral dopants for liquid crystal applications ZYMERGEN INC. (US) 2023-11-14 US claimed
US-20230203378-A1 FORMULATIONS OF BIOREACHABLE DOPANTS FOR LIQUID CRYSTALS KENT STATE UNIVERSITY 2023-06-29 US claimed
US-20220025267-A1 BIOREACHABLE CHIRAL DOPANTS FOR LIQUID CRYSTAL APPLICATIONS ZYMERGEN ACQUISITION SUB, INC. 2022-01-27 US claimed
WO-2020159620-A9 BIOREACHABLE CHIRAL DOPANTS FOR LIQUID CRYSTAL APPLICATIONS ZYMERGEN INC. (US) 2020-10-22 WO claimed
CN-111606784-A Synthetic method of 4, 4' -dihydroxybiphenyl 安徽中羰碳一工业技术有限责任公司 2020-09-01 CN claimed
US-6602562-B2 High dielectric anisotropy and clearing point with little impact on voltage holding ratio, low temperature stability and response time MERCK PATENT GESELLSCHAFT MIT (DE) 2003-08-05 US claimed
US-20030113482-A1 Realignment layer; field has a component parallel to the liquid-crystal layer; positive dielectric anisotropy MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2003-06-19 US claimed
US-6217792-B1 Chiral dopants MERCK PATENT GMBH (DE) 2001-04-17 US claimed
US-6118422-A Light scattering type liquid crystal display device, and method for driving it CHISSO CORPORATION (JP) 2000-09-12 US claimed
US-5679282-A Chiral 2,6-difluorobenzene derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1997-10-21 US claimed
EP-0408995-B1 Liquid crystal medium with limited temperature-dependence of the d/p coefficient MERCK PATENT GMBH (DE) 1995-11-08 EP claimed
US-5139698-A Achiral liquid crystal compound with doping component MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1992-08-18 US claimed
US-5043093-A Liquid crystals MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-08-27 US claimed
EP-0152808-B1 NITROGEN CONTAINING HETEROCYCLES MERCK PATENT GmbH (DE) 1990-09-12 EP claimed
EP-0209622-B1 HYDROTERPHENYLS MERCK PATENT GmbH (DE) 1989-06-07 EP claimed
US-4702562-A MIXTURE-FOR MULTIPLEXING MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1987-10-27 US claimed
US-4419264-A Fluorine-containing 4,4'-bis-(cyclohexyl)-biphenyl derivatives, and dielectrics and electro-optical display elements containing them MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1983-12-06 US claimed
US-4398803-A Liquid crystal display element MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1983-08-16 US claimed
US-4366080-A Liquid crystal display element TOKYO SHIBAURA DENKI KABUSHIKI KAISHA (JP) 1982-12-28 US claimed