Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 11/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5914436 | 1.00 | CARM1 (0.40) | CARM1ALDH1A1CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL5914143 | 0.86 | SMN1; SMN2 (0.39) | ALDH1A1CYP3A4TSHRSMN1; SMN2CYP1A2 | |
| SCHEMBL5914118 | 0.86 | MAPK14 (0.42) | ALDH1A1CYP3A4TSHRSMN1; SMN2CYP1A2 | |
| SCHEMBL5913787 | 0.83 | MAPK14 (0.41) | TSHRSMN1; SMN2MAPK14MAPTKMT2A | |
| SCHEMBL5913794 | 0.83 | MAPK14 (0.41) | TSHRSMN1; SMN2MAPK14MAPTKMT2A | |
| SCHEMBL5913917 | 0.81 | CLK4 (0.43) | ALDH1A1CYP3A4TSHRSMN1; SMN2CYP1A2 | |
| SCHEMBL5913924 | 0.81 | CLK4 (0.43) | ALDH1A1CYP3A4TSHRSMN1; SMN2CYP1A2 | |
| SCHEMBL5914289 | 0.81 | CARM1 (0.38) | CARM1MAPK14KDR | |
| SCHEMBL5914294 | 0.81 | CARM1 (0.38) | CARM1MAPK14KDR | |
| SCHEMBL5914093 | 0.80 | MAPK14 (0.39) | ALDH1A1CYP3A4TSHRSMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060069110-A1 | Substituted heterocyclic compounds and methods of use | AMGEN INC. | 2006-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060069110-A1 | Substituted heterocyclic compounds and methods of use | MAPT, MYLK2, IAPP | CARM1 1751/4885ALDH1A1 3019/4885CYP3A4 1290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.