Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | RECQL | P46063 | 1/20 | 0.72 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.70 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.62 |
| ▸ | F3 | P13726 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 3/20 | 0.58 |
| ▸ | MAOA | P21397 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5915510 | 1.00 | MAPT (0.72) | MAPTKDM4EALDH1A1RECQLKEAP1 | |
| SCHEMBL5915375 | 1.00 | MAPT (0.72) | MAPTKDM4EALDH1A1RECQLKEAP1 | |
| SCHEMBL5915521 | 0.88 | F3 (0.64) | MAPTKDM4EALDH1A1RECQLF3 | |
| SCHEMBL5915515 | 0.88 | F3 (0.64) | MAPTKDM4EALDH1A1RECQLF3 | |
| SCHEMBL5915758 | 0.88 | F3 (0.64) | MAPTKDM4EALDH1A1RECQLF3 | |
| SCHEMBL25192237 | 0.84 | MAPT (0.78) | MAPTKDM4EALDH1A1RECQLKEAP1 | |
| SCHEMBL16498460 | 0.84 | MAPT (0.81) | MAPTKDM4EALDH1A1RECQLKEAP1 | |
| SCHEMBL30383808 | 0.84 | MAPT (0.78) | MAPTKDM4EALDH1A1RECQLKEAP1 | |
| SCHEMBL16498462 | 0.84 | MAPT (0.81) | MAPTKDM4EALDH1A1RECQLKEAP1 | |
| SCHEMBL31233174 | 0.84 | MAPT (0.81) | MAPTKDM4EALDH1A1RECQLKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060052600-A1 | Amino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2006-03-09 | — | — | US | claimed |
| US-20060052600-A1 | Amino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2006-03-09 | — | — | US | disclosed |