SCHEMBL591663

SCHEMBL591663

CN(C)c1cccc2c(S(=O)(=O)NCCCCCCCCCCC(=O)O)cccc12

nearest known ligand 0.79

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.79
HDAC10 Q969S8 1/20 0.79
HDAC6 Q9UBN7 1/20 0.79
HDAC5 Q9UQL6 1/20 0.79
GBA1 P04062 3/20 0.61
GLB1 P16278 3/20 0.60
FABP4 P15090 4/20 0.60
FUCA1 P04066 1/20 0.57
EPHX2 P34913 1/20 0.55
ALDH1A1 P00352 1/20 0.55
LMNA P02545 1/20 0.55
THRB P10828 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
MEN1 O00255 1/20 0.53
POLB P06746 1/20 0.53
KMT2A Q03164 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
TBXA2R P21731 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18257191 1.00 HDAC4 (0.79) HDAC4HDAC10HDAC6HDAC5GBA1
SCHEMBL15515796 1.00 HDAC4 (0.79) HDAC4HDAC10HDAC6HDAC5GBA1
SCHEMBL1712988 1.00 HDAC4 (0.79) HDAC4HDAC10HDAC6HDAC5GBA1
SCHEMBL15515613 1.00 HDAC4 (0.79) HDAC4HDAC10HDAC6HDAC5GBA1
SCHEMBL15507473 1.00 HDAC4 (0.79) HDAC4HDAC10HDAC6HDAC5GBA1
SCHEMBL29524676 1.00 HDAC4 (0.79) HDAC4HDAC10HDAC6HDAC5GBA1
SCHEMBL13004448 0.99 HDAC4 (0.77) HDAC4HDAC10HDAC6HDAC5GBA1
SCHEMBL5148215 0.95 HDAC4 (0.71) HDAC4HDAC10HDAC6HDAC5GBA1
SCHEMBL8016351 0.91 HDAC4 (0.79) HDAC4HDAC10HDAC6HDAC5GBA1
SCHEMBL15259321 0.91 HDAC4 (0.79) HDAC4HDAC10HDAC6HDAC5GBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2114462-B1 Compounds for fluorescence imaging UNIV GENEVE (CH) 2013-06-05 EP claimed
US-20100278745-A1 COMPOUNDS FOR FLUORESCENCE IMAGING UNIVERSITE DE GENEVE (CH) 2010-11-04 US claimed
EP-0576480-B1 ASSAY FOR THE DETERMINATION OF ESTER SUBSTRATES BRITISH TECH GROUP (GB) 1998-06-03 EP claimed
US-5512429-A Assay for enzyme activity BRITISH TECHNOLOGY GROUP LIMITED (GB) 1996-04-30 US claimed
EP-0493426-B1 ASSAY FOR ENZYME ACTIVITY BRITISH TECH GROUP (GB) 1995-11-08 EP claimed
US-5449607-A Assay for the quantitative determination of substrates capable of undergoing enzymatic hydrolysis to release long-chain fatty acids BRITISH TECHNOLOGY GROUP LIMITED (GB) 1995-09-12 US claimed
EP-0576480-A1 ASSAY FOR THE DETERMINATION OF ESTER SUBSTRATES BRITISH TECHNOLOGY GROUP LTD (GB) 1994-01-05 EP claimed
WO-1992016847-A1 ASSAY FOR THE DETERMINATION OF ESTER SUBSTRATES BRITISH TECHNOLOGY GROUP LTD (GB) 1992-10-01 WO claimed
WO-1991004338-A1 ASSAY FOR ENZYME ACTIVITY BRITISH TECHNOLOGY GROUP PLC (GB) 1991-04-04 WO claimed
CN-117907494-A Application of D-2-phosphoglycerate and L-propionyl carnitine in judging whether female buffalo is in oestrus 中国农业科学院北京畜牧兽医研究所 2024-04-19 CN disclosed
US-11150358-B2 Radiation dosimetry sol or gel and radiation dosimeter comprising same as material for radiation dosimetry RIKEN (JP) 2021-10-19 US disclosed
US-20200333474-A1 RADIATION DOSIMETRY SOL OR GEL AND RADIATION DOSIMETER COMPRISING SAME AS MATERIAL FOR RADIATION DOSIMETRY RIKEN (JP) 2020-10-22 US disclosed
EP-3686632-A1 RADIATION DOSIMETRY SOL OR GEL AND RADIATION DOSIMETER COMPRISING SAME AS MATERIAL FOR RADIATION DOSIMETRY Riken (JP) 2020-07-29 EP disclosed
US-10443081-B2 Methods for the expression of peptides and proteins NUMAFERM GMBH (DE) 2019-10-15 US disclosed
US-5512429-A Assay for enzyme activity BRITISH TECHNOLOGY GROUP LIMITED (GB) 1996-04-30 US disclosed
US-5512490-A SUPPORT, ARRAY OF HETEROGENEOUS SEMISELECTIVE THIN FILMS WHICH FUNCTION AS SENSING RECEPTOR UNITS TRUSTEES OF TUFTS COLLEGE (US) 1996-04-30 US disclosed
EP-0493426-B1 ASSAY FOR ENZYME ACTIVITY BRITISH TECH GROUP (GB) 1995-11-08 EP disclosed
US-5449607-A Assay for the quantitative determination of substrates capable of undergoing enzymatic hydrolysis to release long-chain fatty acids BRITISH TECHNOLOGY GROUP LIMITED (GB) 1995-09-12 US disclosed
US-5244813-A Fiber optic sensor, apparatus, and methods for detecting an organic analyte in a fluid or vapor sample TRUSTEES OF TUFTS COLLEGE (US) 1993-09-14 US disclosed
WO-1991004338-A1 ASSAY FOR ENZYME ACTIVITY BRITISH TECHNOLOGY GROUP PLC (GB) 1991-04-04 WO disclosed