Quinazoline

Quinazoline

SCHEMBL5920

c1ccc2ncncc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
EGFR P00533 9/20 1.00
PIK3CD O00329 1/20 0.61
PIK3CA P42336 1/20 0.61
ALDH1A1 P00352 2/20 0.48
CYP1A2 P05177 1/20 0.45
PDGFRB P09619 1/20 0.44
PDGFRA P16234 1/20 0.44
KDM4E B2RXH2 1/20 0.43
GPR3 P46089 1/20 0.43
TDO2 P48775 2/20 0.42
CYP2A6 P11509 1/20 0.41
MAPT P10636 2/20 0.41
GLA P06280 1/20 0.40
HPGD P15428 1/20 0.40
ACHE P22303 1/20 0.40
IMPDH2 P12268 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinazoline SCHEMBL29490398 1.00 EGFR (1.00) EGFRPIK3CDPIK3CAALDH1A1CYP1A2
Quinazoline SCHEMBL29356169 1.00 EGFR (1.00) EGFRPIK3CDPIK3CAALDH1A1CYP1A2
Quinazoline SCHEMBL22833783 1.00 EGFR (1.00) EGFRPIK3CDPIK3CAALDH1A1CYP1A2
Quinazoline SCHEMBL4487630 0.98 EGFR (0.95) EGFRPIK3CDPIK3CAALDH1A1CYP1A2
Quinazoline SCHEMBL21055790 0.98 EGFR (0.95) EGFRPIK3CDPIK3CAALDH1A1CYP1A2
Quinazoline SCHEMBL5579413 0.98 EGFR (0.95) EGFRPIK3CDPIK3CAALDH1A1CYP1A2
Quinazoline SCHEMBL1119374 0.98 EGFR (0.95) EGFRPIK3CDPIK3CAALDH1A1CYP1A2
Quinazoline SCHEMBL19877280 0.98 EGFR (0.95) EGFRPIK3CDPIK3CAALDH1A1CYP1A2
Quinazoline SCHEMBL8857950 0.98 EGFR (0.95) EGFRPIK3CDPIK3CAALDH1A1CYP1A2
SCHEMBL3196932 0.98 EGFR (0.95) EGFRPIK3CDPIK3CAALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 134401 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6362369-B1 None US claimed
US-20260150572-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2026-05-28 US claimed
US-20260150489-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2026-05-28 US claimed
US-20260146168-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2026-05-28 US claimed
US-20260146124-A1 RESIN COMPOSITION AND USES OF THE SAME TAIWAN UNION TECHNOLOGY CORPORATION (TW) 2026-05-28 US claimed
US-20260150490-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2026-05-28 US claimed
CN-122080075-A Organometallic compound, organic light-emitting device including the same, and electronic apparatus including the organic light-emitting device 2026-05-26 CN claimed
CN-122080076-A Organometallic compound, organic light-emitting device including the same, and electronic apparatus including the organic light-emitting device 2026-05-26 CN claimed
CN-115696943-B Organic electroluminescent device and photoelectric product thereof NINGBO LUMILAN ADVANCED MATERIALS Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122071498-A Organic electroluminescent material and device 环球展览公司 2026-05-22 CN claimed
US-4102885-A Process for preparing 2,4-dihaloquinazolines BRISTOL-MYERS COMPANY (US) 1978-07-25 US claimed
US-4098788-A Process for preparing quinazolines BRISTOL-MYERS COMPANY (US) 1978-07-04 US claimed
US-4096144-A Process for preparing quinazolinone derivatives and their 2-(N-mono-substituted amino)-phenyl ketone intermediate derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1978-06-20 US claimed
US-4046705-A CONTAINING INORGANIC PEROXIDE KAO SOAP CO., LTD. (JA) 1977-09-06 US claimed
US-3998951-A Substituted 2-arylquinazolines as fungicides FMC CORPORATION (US) 1976-12-21 US claimed
US-3980650-A 4-Amino-pyrimidine derivatives N.V. KONINKLIJKE PHARMACEUTISCHE FABRIEKEN V/H BROCADES-STHEEMAN EN PHARMACIA (NL) 1976-09-14 US claimed
US-3970630-A 2,4-Quinazoline dione-polyamide-ester resins INSTITUT FRANCAIS DU PETROLE, ES CARBURANTS ET LUBRIFIANTS ET ENTREPRISE DE RECHERCHES ET D'ACTIVITIES PETROLIERS ELF (FR) 1976-07-20 US claimed
US-3962444-A Use of 4-thiocyano-quinazolines as fungicides U.S. PHILIPS CORPORATION (US) 1976-06-08 US claimed
US-3959100-A OPACIFIER SCM CORPORATION (US) 1976-05-25 US claimed
US-3950526-A Quinazoline derivatives in pharmaceutical compositions for treating pain and inflammation SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-04-13 US claimed