Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL5929671

CCc1c(CO)cccc1Nc1c(C(N)=O)cnc2cc(OCCCN(C)C)c(OC)cc12.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CSF1R P07333 20/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL5929986 0.96 CSF1R (0.57) CSF1R
SCHEMBL5929912 0.95 CSF1R (0.56) CSF1R
Trifluoroacetic Acid SCHEMBL5929686 0.94 CSF1R (0.52) CSF1R
Trifluoroacetic Acid SCHEMBL5929716 0.91 CSF1R (0.59) CSF1R
SCHEMBL5929961 0.91 CSF1R (0.60) CSF1R
Trifluoroacetic Acid SCHEMBL4914332 0.90 CSF1R (0.52) CSF1R
Trifluoroacetic Acid SCHEMBL4905506 0.89 CSF1R (0.53) CSF1R
Trifluoroacetic Acid SCHEMBL5930188 0.89 CSF1R (0.52) CSF1R
SCHEMBL4905636 0.88 CSF1R (0.54) CSF1R
SCHEMBL5929940 0.88 CSF1R (0.56) CSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060173034-A1 Novel 4-anilinoquinoline-3-carboxamides ASTRAZENECA AB (SE) 2006-08-03 — — US disclosed
US-7037925-B2 4-anilinoquinoline-3-carboxamides ASTRAZENECA AB (SE) 2006-05-02 — — US disclosed
EP-1387830-A1 NOVEL 4-ANILINOQUINOLINE-3-CARBOXAMIDES AstraZeneca AB (SE) 2004-02-11 — — EP disclosed
WO-2002092571-A1 NOVEL 4-ANILINOQUINOLINE-3-CARBOXAMIDES ASTRAZENECA AB (SE) 2002-11-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060173034-A1 Novel 4-anilinoquinoline-3-carboxamides JAK3, JAK2, JAK1 CSF1R 889/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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