⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5934305 | 1.00 | — | — | |
| SCHEMBL8467424 | 0.78 | — | — | |
| SCHEMBL4031275 | 0.74 | FFAR3 (0.35) | — | |
| SCHEMBL4031277 | 0.74 | FFAR3 (0.35) | — | |
| SCHEMBL8615746 | 0.70 | — | — | |
| SCHEMBL13688280 | 0.69 | FFAR3 (0.41) | — | |
| SCHEMBL9639839 | 0.69 | NPSR1 (0.32) | — | |
| SCHEMBL9784921 | 0.69 | NPSR1 (0.32) | — | |
| SCHEMBL11522215 | 0.67 | FFAR3 (0.35) | — | |
| SCHEMBL21950869 | 0.66 | CYP2C19 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060122203-A1 | 2-Hydroxymethylcyclopropylidenemethylpurines and - pyrimidines as antiviral agents | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2006-06-08 | — | — | US | disclosed |
| US-6958345-B2 | 2-hydroxymethylcyclopropylidene methylpurines and -pyrimidines as antiviral agents | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2005-10-25 | — | — | US | disclosed |
| US-20050009842-A1 | 2-hydroxymethylcyclopropylidene methylpurines and -pyrimidines as antiviral agents | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2005-01-13 | — | — | US | disclosed |
| US-6790841-B2 | FOR THERAPY OF MAMMAL INFECTED WITH VIRUS | WAYNE STATE UNIVERSITY | 2004-09-14 | — | — | US | disclosed |
| US-20020193353-A1 | 2-hydroxymethylcyclopropylidenemethylpurines and -pyrimidines as antiviral agents | WAYNE STATE UNIVERSITY | 2002-12-19 | — | — | US | disclosed |
| US-6352991-B1 | VIRICIDES FOR TREATMENT OF AIDS | WAYNE STATE UNIVERSITY | 2002-03-05 | — | — | US | disclosed |