Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12236 | 0.85 | — | — | |
| SCHEMBL11899084 | 0.81 | SLC6A2 (0.59) | SLC6A2MMP12MMP13 | |
| SCHEMBL10457 | 0.80 | — | — | |
| SCHEMBL11961989 | 0.80 | SLC6A2 (0.59) | SLC6A2MMP12MMP13 | |
| SCHEMBL11044 | 0.80 | — | — | |
| SCHEMBL5795 | 0.80 | — | — | |
| SCHEMBL6138 | 0.79 | SLC6A2 (0.46) | SLC6A2MMP12MMP13 | |
| SCHEMBL6078 | 0.78 | SLC6A2 (0.47) | SLC6A2MMP12MMP13 | |
| SCHEMBL6204 | 0.77 | SLC6A2 (0.46) | SLC6A2MMP12MMP13 | |
| SCHEMBL5951 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488489-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | Pfizer Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011045703-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2011-04-21 | — | — | WO | disclosed |