SCHEMBL5936705

SCHEMBL5936705

Cc1ccc(-c2ccc(C)c(C(F)(F)F)c2)cc1C

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.49
S1PR1 P21453 5/20 0.47
PDE3B Q13370 1/20 0.45
PDE3A Q14432 1/20 0.45
AR P10275 5/20 0.44
CTSS P25774 1/20 0.42
CTSK P43235 1/20 0.42
MCL1 Q07820 1/20 0.39
RXRA P19793 1/20 0.39
RXRB P28702 1/20 0.39
ALDH1A1 P00352 1/20 0.38
CYP3A4 P08684 1/20 0.38
TSHR P16473 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
PGR P06401 1/20 0.38
KIF11 P52732 2/20 0.37
TAS2R14 Q9NYV8 1/20 0.36
ALPL P05186 1/20 0.36
ALPI P09923 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5936706 0.98 NOTUM (0.47) NOTUMS1PR1PDE3BPDE3AAR
SCHEMBL5949403 0.93 NOTUM (0.53) NOTUMS1PR1PDE3BPDE3AAR
SCHEMBL30742956 0.93 NOTUM (0.53) NOTUMS1PR1PDE3BPDE3AAR
SCHEMBL30742957 0.93 NOTUM (0.53) NOTUMS1PR1PDE3BPDE3AAR
SCHEMBL5949422 0.91 AR (0.52) NOTUMS1PR1PDE3BPDE3AAR
SCHEMBL18947651 0.89 S1PR1 (0.44) NOTUMS1PR1PDE3BPDE3AAR
SCHEMBL18947663 0.87 NOTUM (0.43) NOTUMS1PR1PDE3BPDE3AAR
SCHEMBL18947647 0.86 S1PR1 (0.52) NOTUMS1PR1PDE3BPDE3AAR
SCHEMBL17297890 0.85 AR (0.61) NOTUMS1PR1PDE3BPDE3AAR
SCHEMBL18947661 0.85 S1PR1 (0.45) NOTUMS1PR1PDE3BPDE3AAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9868823-B2 Display device, method for manufacturing same, polyimide film for display device supporting bases, and method for producing polyimide film for display device supporting bases NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2018-01-16 US disclosed
US-20170240707-A1 DISPLAY DEVICE, METHOD FOR MANUFACTURING SAME, POLYIMIDE FILM FOR DISPLAY DEVICE SUPPORTING BASES, AND METHOD FOR PRODUCING POLYIMIDE FILM FOR DISPLAY DEVICE SUPPORTING BASES NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2017-08-24 US disclosed
US-9695283-B2 Display device, method for manufacturing same, polyimide film for display device supporting bases, and method for producing polyimide film for display device supporting bases NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2017-07-04 US disclosed
US-20160244565-A1 DISPLAY DEVICE, METHOD FOR MANUFACTURING SAME, POLYIMIDE FILM FOR DISPLAY DEVICE SUPPORTING BASES, AND METHOD FOR PRODUCING POLYIMIDE FILM FOR DISPLAY DEVICE SUPPORTING BASES NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2016-08-25 US disclosed
US-9403947-B2 Display device, method for manufacturing same, polyimide film for display device supporting bases, and method for producing polyimide film for display device supporting bases NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2016-08-02 US disclosed
US-20160168329-A1 POLYMIDE RESIN MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2016-06-16 US disclosed
US-20150183932-A1 DISPLAY DEVICE, METHOD FOR MANUFACTURING SAME, POLYIMIDE FILM FOR DISPLAY DEVICE SUPPORTING BASES, AND METHOD FOR PRODUCING POLYIMIDE FILM FOR DISPLAY DEVICE SUPPORTING BASES NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-07-02 US disclosed
US-20120107725-A1 Solid Polymer Electrolyte Composition, and Ion-Exchange Membrane, Membrane Electrode Assembly and Fuel Cell TOYO BOSEKI KABUSHIKI KAISHA (JP) 2012-05-03 US disclosed