Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6386269 | 0.77 | HTR2A (0.50) | ANPEPCYP19A1CYP2D6 | |
| SCHEMBL4238327 | 0.72 | TYMS (0.37) | CYP19A1CYP2D6 | |
| SCHEMBL31114626 | 0.72 | CYP19A1 (0.43) | CYP19A1CYP2D6TBXAS1TRPM8 | |
| SCHEMBL14578648 | 0.72 | CYP19A1 (0.43) | CYP19A1CYP2D6TBXAS1TRPM8 | |
| SCHEMBL1266396 | 0.72 | CYP19A1 (0.43) | CYP19A1CYP2D6TBXAS1TRPM8 | |
| SCHEMBL31114621 | 0.72 | CYP19A1 (0.43) | CYP19A1CYP2D6TBXAS1TRPM8 | |
| SCHEMBL14578647 | 0.72 | CYP19A1 (0.43) | CYP19A1CYP2D6TBXAS1TRPM8 | |
| Hydrochloric Acid SCHEMBL22031926 | 0.70 | CYP19A1 (0.42) | CYP19A1CYP2D6TBXAS1TRPM8 | |
| Hydrochloric Acid SCHEMBL31365166 | 0.70 | CYP19A1 (0.42) | CYP19A1CYP2D6TBXAS1TRPM8 | |
| Hydrochloric Acid SCHEMBL26962733 | 0.70 | CYP19A1 (0.42) | CYP19A1CYP2D6TBXAS1TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060079495-A1 | Diagnosis and treatment system for \"reward deficiency syndrome\" (RDS) and related behaviors | SYNAPTAMINE, INC. | 2006-04-13 | — | — | US | disclosed |
| US-6955873-B1 | Diagnosis and treatment system for reward deficiency syndrome (RDS) and related behaviors | SYNAPTAMINE, INC. | 2005-10-18 | — | — | US | disclosed |
| US-6132724-A | Allelic polygene diagnosis of reward deficiency syndrome and treatment | CITY OF HOPE NATIONAL MEDICAL CENTER (US) | 2000-10-17 | — | — | US | disclosed |
| EP-0979092-A2 | ALLELIC POLYGENE DIAGNOSIS OF REWARD DEFICIENCY SYNDROME AND TREATMENT | Kenneth Blum, Inc. (US) | 2000-02-16 | — | — | EP | disclosed |
| WO-1998048785-A9 | ALLELIC POLYGENE DIAGNOSIS OF REWARD DEFICIENCY SYNDROME AND TREATMENT | KENNETH BLUM INC (US) | 1999-05-20 | — | — | WO | disclosed |
| WO-1998048785-A2 | ALLELIC POLYGENE DIAGNOSIS OF REWARD DEFICIENCY SYNDROME AND TREATMENT | KENNETH BLUM, INC. (US) | 1998-11-05 | — | — | WO | disclosed |