⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL164800 | 1.00 | — | — | |
| SCHEMBL19862759 | 1.00 | — | — | |
| SCHEMBL21641518 | 1.00 | — | — | |
| SCHEMBL6848938 | 1.00 | — | — | |
| SCHEMBL161194 | 1.00 | — | — | |
| SCHEMBL574756 | 1.00 | — | — | |
| SCHEMBL9271747 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL31757671 | 0.97 | CYP1A2 (0.39) | — | |
| Hydrochloric Acid SCHEMBL31757860 | 0.97 | CYP1A2 (0.39) | — | |
| SCHEMBL723877 | 0.80 | CYP2D6 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7206793-A | — | — | None | — | — | JP | disclosed |
| US-8748375-B2 | Methods for affecting body composition using amylin agonists | AMYLIN PHARMACEUTICALS, LLC (US) | 2014-06-10 | — | — | US | disclosed |
| EP-1814590-B2 | TREATMENT OF OBESITY AND RELATED DISORDERS | AMYLIN PHARMACEUTICALS INC (US) | 2013-12-11 | — | — | EP | disclosed |
| US-8598120-B2 | Methods for treatment using amylin family peptides | AMYLIN PHARMACEUTICALS, LLC (US) | 2013-12-03 | — | — | US | disclosed |
| US-8394765-B2 | Methods of treating obesity with two different anti-obesity agents | AMYLIN PHARMACEUTICALS LLC (US) | 2013-03-12 | — | — | US | disclosed |
| US-20120196796-A1 | AMYLIN FAMILY PEPTIDES AND METHODS FOR MAKING AND USING THEM | AMYLIN PHARMACEUTICALS, INC. (US) | 2012-08-02 | — | — | US | disclosed |
| US-20120071401-A1 | AMYLIN AGONIST COMPOUNDS FOR ESTROGEN-DEFICIENT MAMMALS | Amylin Pharamaceuticals, Inc. (US) | 2012-03-22 | — | — | US | disclosed |
| US-20120053118-A1 | METHODS FOR AFFECTING BODY COMPOSITION USING AMYLIN AGONISTS | AMYLIN PHARMACEUTICALS, INC. (US) | 2012-03-01 | — | — | US | disclosed |
| EP-2416797-A2 | AMYLIN AGONIST COMPOUNDS FOR ESTROGEN-DEFICIENT MAMMALS | Amylin Pharmaceuticals, Inc. (US) | 2012-02-15 | — | — | EP | disclosed |
| US-8114958-B2 | Therapy for metabolism disorders; obesity; diabetes; cardovascular disordrs; eating disorders; hypoglycemic agents; hypotensive agents; dyslipidemia; sleep disorders; respiraotry system disorders; osteoarthritis; insulin resistance | AMYLIN PHARMACEUTICALS, INC. (US) | 2012-02-14 | — | — | US | disclosed |
| US-20080274952-A1 | Amylin Family Peptides And Methods For Making And Using Them | AMYLIN PHARMACEUTICALS, INC. (US) | 2008-11-06 | — | — | US | disclosed |
| US-20080207512-A1 | Methods for Treating Obesity and Obesity Related and Disorders | AMYLIN PHARMACEUTICALS, INC. (US) | 2008-08-28 | — | — | US | disclosed |
| EP-1954313-A1 | TREATMENT OF OBESITY AND RELATED DISORDERS | Amylin Pharmaceuticals, Inc. (US) | 2008-08-13 | — | — | EP | disclosed |
| EP-1814590-A2 | TREATMENT OF OBESITY AND RELATED DISORDERS | Amylin Pharmaceuticals, Inc. (US) | 2007-08-08 | — | — | EP | disclosed |
| WO-2007055743-A2 | TREATMENT OF OBESITY AND RELATED DISORDERS | AMYLIN PHARMACEUTICALS, INC. (US) | 2007-05-18 | — | — | WO | disclosed |
| WO-2007055728-A1 | TREATMENT OF OBESITY AND RELATED DISORDERS | AMYLIN PHARMACEUTICALS, INC. (US) | 2007-05-18 | — | — | WO | disclosed |
| EP-1716172-A1 | AMYLIN FAMILY PEPTIDES AND METHODS FOR MAKING AND USING THEM | Amylin Pharmaceuticals, Inc. (US) | 2006-11-02 | — | — | EP | disclosed |
| WO-2006083254-A1 | AMYLIN FAMILY PEPTIDES AND METHODS FOR MAKING AND USING THEM | AMYLIN PHARMACEUTICALS, INC. (US) | 2006-08-10 | — | — | WO | disclosed |
| WO-2006052608-A2 | TREATMENT OF OBESITY AND RELATED DISORDERS | AMYLIN PHARMACEUTICALS, INC. (US) | 2006-05-18 | — | — | WO | disclosed |
| JP-H07206793-A | OPTICALLY ACTIVE 2-METHYLTHREONINE, 2-METHYLALLOTHREONINE AND ITS PRODUCTION | SUNTORY LTD | 1995-08-08 | — | — | JP | disclosed |