Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 3/20 | 0.49 |
| ▸ | CNR2 | P34972 | 3/20 | 0.49 |
| ▸ | IDO1 | P14902 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TTK | P33981 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28880065 | 0.98 | RARG (0.51) | RARGKDM4EGAAPDPK1CYP3A4 | |
| SCHEMBL460612 | 0.81 | RARG (0.68) | RARGKDM4EGAAPDPK1CYP3A4 | |
| SCHEMBL31134461 | 0.78 | CNR1 (0.59) | RARGKDM4EGAAPDPK1CYP3A4 | |
| SCHEMBL1966860 | 0.78 | CNR1 (0.59) | RARGKDM4EGAAPDPK1CYP3A4 | |
| SCHEMBL4193104 | 0.76 | RARG (0.53) | RARGKDM4EGAAPDPK1CYP3A4 | |
| SCHEMBL4057113 | 0.74 | RARG (0.60) | RARGKDM4EGAAPDPK1CYP3A4 | |
| SCHEMBL8430557 | 0.73 | CNR1 (0.59) | RARGKDM4EGAAPDPK1CYP3A4 | |
| SCHEMBL21965345 | 0.73 | RARG (0.50) | RARGKDM4EGAAPDPK1CYP3A4 | |
| SCHEMBL4193108 | 0.73 | RARG (0.50) | RARGKDM4EGAAPDPK1CYP3A4 | |
| SCHEMBL31073819 | 0.73 | CNR2 (0.58) | RARGKDM4EGAAPDPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060247124-A1 | Polymerisation reaction and catalyst therefor | JOHNSON MATTHEY PLC (GB) | 2006-11-02 | — | — | US | disclosed |
| EP-1569996-A1 | POLYMERISATION REACTION AND CATALYST THEREFOR | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2005-09-07 | — | — | EP | disclosed |
| WO-2004052980-A1 | POLYMERISATION REACTION AND CATALYST THEREFOR | JOHNSON MATTHEY PLC (GB) | 2004-06-24 | — | — | WO | disclosed |