Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 18/20 | 0.67 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP2J2 | P51589 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5948021 | 0.92 | EPHX2 (0.79) | EPHX2CYP2C9CYP2C19CYP2J2NPC1 | |
| SCHEMBL5947734 | 0.87 | EPHX2 (0.67) | EPHX2CYP2C9CYP2C19CYP2J2NPC1 | |
| SCHEMBL5947835 | 0.81 | EPHX2 (0.60) | EPHX2CYP2C9CYP2C19CYP2J2ALOX5 | |
| SCHEMBL5947879 | 0.81 | EPHX2 (0.60) | EPHX2CYP2C9CYP2C19CYP2J2ALOX5 | |
| SCHEMBL5948102 | 0.81 | EPHX2 (1.00) | EPHX2TPSAB1CYP2C9CYP2C19NPC1 | |
| SCHEMBL5948057 | 0.81 | EPHX2 (0.68) | EPHX2CYP2C9CYP2C19CYP2J2 | |
| SCHEMBL5948076 | 0.81 | EPHX2 (0.91) | EPHX2CYP2C9CYP2C19CYP2J2ALOX5 | |
| SCHEMBL5947660 | 0.80 | EPHX2 (0.76) | EPHX2CYP2C9CYP2C19CYP2J2 | |
| SCHEMBL5948050 | 0.79 | EPHX2 (1.00) | EPHX2CYP2C9CYP2C19CYP2J2ALOX5 | |
| SCHEMBL4638764 | 0.79 | EPHX2 (0.87) | EPHX2TPSAB1CYP2C9CYP2C19NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276515-A1 | Soluble Epoxide Hydrolase Inhibitors and Methods of Using Same | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276515-A1 | Soluble Epoxide Hydrolase Inhibitors and Methods of Using Same | EPHX1, EPHX2, NCEH1 | EPHX2 2/4885TPSAB1 615/4885CYP2C9 477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.